Recombinant Human CD58 Protein, His-tagged

• Cat.No.: CD58-246H
• Product Overview: Recombinant Human CD58(26-524aa) fused with His tag at C-terminal was expressed in Insect cells.

Specification

• Description: CD58, also known as lymphocyte function-associated antigen 3 isoform 1, is a cell adhesion molecule expressed on Antigen Presenting Cells (APC), particularly macrophages. It binds to CD2 (LFA-2) on T cells and is important in strengthening the adhesion between the T cells and Professional Antigen Presenting Cells. It is an important regulator of immune cell function which occurs as both surface-associated and soluble forms. It is associated with increased risk for multiple sclerosis.
• Source: Insect cells
• Species: Human
• Tag: His
• Predicted N Terminal: Ala
• Form: Liquid. In Phosphate Buffered Saline (pH 7.4) containing 10% glycerol.
• Molecular Mass: 22.5kDa (196aa) 28-40kDa (SDS-PAGE under reducing conditions)
• Protein length: 26-524aa
• AA Sequence: ADPFSQQIYG VVYGNVTFHV PSNVPLKEVL WKKQKDKVAE LENSEFRAFS SFKNRVYLDT VSGSLTIYNL TSSDEDEYEM ESPNITDTMK
  FFLYVLESLP SPTLTCALTN GSIEVQCMIP EHYNSHRGLI MYSWDCPMEQ CKRNSTSIYF KMENDLPQKI QCTLSNPLFN TTSSIILTTC
  IPSSGHSRHR HHHHHH
• Purity: > 95% by SDS - PAGE
• Applications: SDS-PAGE
• Storage: Can be stored at +4 centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20 centigrade or -70 centigrade. Avoid repeated freezing and thawing cycles.
• Concentration: 1mg/ml (determined by Absorbance at 280nm)

Gene Information

• Gene Name: CD58 CD58 molecule [ Homo sapiens ]
• Official Symbol: CD58
• Synonyms: CD58; CD58 molecule; CD58 antigen, (lymphocyte function associated antigen 3) , LFA3; lymphocyte function-associated antigen 3; surface glycoprotein LFA-3; CD58 antigen, (lymphocyte function-associated antigen 3); ag3; LFA3; LFA-3; FLJ23181; FLJ43722
• Gene ID: 965
• mRNA Refseq: NM_001779
• Protein Refseq: NP_001770
• MIM: 153420
• UniProt ID: P19256