Active Recombinant Human CD70 protein, hFc&Avi-tagged, Biotinylated
Cat.No. : | CD70-892H |
Product Overview : | Biotinylated Recombinant Human CD70 protein(NP_001243.1)(Gln39-Pro193), fused with hFc tag and Avi tag, was expressed in HEK293. |
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Source : | HEK293 |
Species : | Human |
Tag : | hFc&Avi |
Form : | Lyophilized from sterile PBS, pH 7.4.Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA. |
Bio-activity : | Immobilized Human CD27 (His & hFc Tag) at 2 μg/mL (100 μL/well) can bind Human CD70 (ECD, hFc & AVI Tag), Biotinylated, the EC50 is 8-68ng/mL. |
Molecular Mass : | The recombinant human CD70 consists of 408 amino acids and predicts a molecular mass of 45.7 kDa. |
Proteinlength : | Gln39-Pro193 |
Endotoxin : | < 1.0 EU per μg protein as determined by the LAL method. |
Purity : | > 80 % as determined by SDS-PAGE. |
Storage : | Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents. |
Gene Name : | CD70 CD70 molecule [ Homo sapiens ] |
Official Symbol : | CD70 |
Synonyms : | CD70; CD70 molecule; CD27LG, TNFSF7, tumor necrosis factor (ligand) superfamily, member 7; CD70 antigen; CD27L; CD27-L; CD27 ligand; Ki-24 antigen; surface antigen CD70; tumor necrosis factor ligand superfamily member 7; tumor necrosis factor (ligand) superfamily, member 7; CD27LG; TNFSF7; |
Gene ID : | 970 |
mRNA Refseq : | NM_001252 |
Protein Refseq : | NP_001243 |
MIM : | 602840 |
UniProt ID : | P32970 |
Products Types
◆ Recombinant Protein | ||
CD70-545H | Recombinant Human CD70 Protein, His (Fc)-Avi-tagged | +Inquiry |
CD70-437H | Recombinant Human CD70 Protein (Gln39-Pro193), RIgG Fc-tagged | +Inquiry |
CD70-206H | Recombinant Human CD70 Protein, C-His-tagged | +Inquiry |
CD70-3100H | Recombinant Human CD70 Protein, MYC/DDK-tagged | +Inquiry |
CD70-623H | Recombinant Human CD70 Protein, Fc-tagged | +Inquiry |
◆ Lysates | ||
CD70-1303RCL | Recombinant Rat CD70 cell lysate | +Inquiry |
CD70-2710HCL | Recombinant Human CD70 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionAntibodies, antibody-drug conjugates, and chimeric antigen receptor (CAR) T-cell therapies are being developed to target CD70 in cancer.
CD70-targeted therapies can enhance the body's immune response against cancer cells and potentially lead to more effective treatments.
CD70 expression is often observed in Hodgkin's lymphoma and certain types of T-cell lymphomas.
Challenges include potential toxicities and finding the right balance to target CD70 effectively without harming normal immune functions.
Yes, there are ongoing clinical trials exploring CD70-targeted therapies for various cancer types.
Customer Reviews (3)
Write a reviewTheir collaboration, expertise, and customized solutions contribute to the successful execution of experiments, reliable data generation, and the advancement of scientific knowledge in the field.
the manufacturer's support is crucial for researchers using CD70 protein in trials.
These resources can enhance the efficiency and accuracy of experimental workflows and contribute to successful outcomes.
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