Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953

Active Recombinant Human CD70 protein, hFc&Avi-tagged, Biotinylated

Cat.No. : CD70-892H
Product Overview : Biotinylated Recombinant Human CD70 protein(NP_001243.1)(Gln39-Pro193), fused with hFc tag and Avi tag, was expressed in HEK293.
Unit
Price
Qty
  • Specification
  • Gene Information
  • Related Products
Source : HEK293
Species : Human
Tag : hFc&Avi
Form : Lyophilized from sterile PBS, pH 7.4.Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.
Bio-activity : Immobilized Human CD27 (His & hFc Tag) at 2 μg/mL (100 μL/well) can bind Human CD70 (ECD, hFc & AVI Tag), Biotinylated, the EC50 is 8-68ng/mL.
Molecular Mass : The recombinant human CD70 consists of 408 amino acids and predicts a molecular mass of 45.7 kDa.
Proteinlength : Gln39-Pro193
Endotoxin : < 1.0 EU per μg protein as determined by the LAL method.
Purity : > 80 % as determined by SDS-PAGE.
Storage : Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents.
Gene Name : CD70 CD70 molecule [ Homo sapiens ]
Official Symbol : CD70
Synonyms : CD70; CD70 molecule; CD27LG, TNFSF7, tumor necrosis factor (ligand) superfamily, member 7; CD70 antigen; CD27L; CD27-L; CD27 ligand; Ki-24 antigen; surface antigen CD70; tumor necrosis factor ligand superfamily member 7; tumor necrosis factor (ligand) superfamily, member 7; CD27LG; TNFSF7;
Gene ID : 970
mRNA Refseq : NM_001252
Protein Refseq : NP_001243
MIM : 602840
UniProt ID : P32970

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

Inquiry

  • Q&As
  • Reviews

Q&As (5)

Ask a question
What are some potential CD70-targeted therapies for cancer? 04/29/2023

Antibodies, antibody-drug conjugates, and chimeric antigen receptor (CAR) T-cell therapies are being developed to target CD70 in cancer.

How can CD70-targeted therapies improve cancer treatment outcomes? 05/03/2022

CD70-targeted therapies can enhance the body's immune response against cancer cells and potentially lead to more effective treatments.

In which hematological malignancies is CD70 expression frequently observed? 04/08/2021

CD70 expression is often observed in Hodgkin's lymphoma and certain types of T-cell lymphomas.

Are there any challenges in developing CD70-targeted therapies for cancer? 03/14/2020

Challenges include potential toxicities and finding the right balance to target CD70 effectively without harming normal immune functions.

Are there clinical trials involving CD70-targeted therapies for cancer treatment? 11/14/2018

Yes, there are ongoing clinical trials exploring CD70-targeted therapies for various cancer types.

Customer Reviews (3)

Write a review
Reviews
05/31/2021

    Their collaboration, expertise, and customized solutions contribute to the successful execution of experiments, reliable data generation, and the advancement of scientific knowledge in the field.

    04/23/2019

      the manufacturer's support is crucial for researchers using CD70 protein in trials.

      03/07/2017

        These resources can enhance the efficiency and accuracy of experimental workflows and contribute to successful outcomes.

        Ask a Question for All CD70 Products

        Required fields are marked with *

        My Review for All CD70 Products

        Required fields are marked with *

        0

        Inquiry Basket

        cartIcon
        logo

        FOLLOW US

        Terms and Conditions        Privacy Policy

        Copyright © 2024 Creative BioMart. All Rights Reserved.

        Contact Us

        • /

        Stay Updated on the Latest Bioscience Trends