Active Recombinant Human CD70 Protein, HA/GCN4-IZ-tagged
Cat.No. : | CD70-218H |
Product Overview : | Recombinant Human CD27 Ligand Protein (Gln39-Pro193) with HA (YPYDVPDYA) tag and GCN4-IZ tag at N-terminus was expressed in human embryonic kidney cell. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis. |
Source : | HEK293 |
Species : | Human |
Tag : | HA/GCN4-IZ |
Form : | Noncovalently-linked homotrimer |
Bio-activity : | Measured by its ability to induce IL-8 secretion in HT1080 human fibrosarcoma cells transfected with human CD27. The ED50 for this effect is 5-25 ng/mL in the presence of Mouse Anti-Hemagglutinin/HA Peptide Monoclonal Antibody. |
Molecular Mass : | 23 kDa |
N-terminal Sequence Analysis : | Tyr |
Endotoxin : | < 0.1 EU/μg of the protein by the LAL method. |
Purity : | > 95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining. |
Storage : | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 centigrade as supplied. 1 month, 2 to 8 centigrade under sterile conditions after reconstitution. 3 months, -20 to -70 centigrade under sterile conditions after reconstitution. |
Storage Buffer : | Lyophilized from a 0.2 μm filtered solution in PBS. |
Reconstitution : | Reconstitute at 200 μg/mL in PBS. |
Shipping : | The product is shipped at ambient temperature. |
Gene Name : | CD70 CD70 molecule [ Homo sapiens (human) ] |
Official Symbol : | CD70 |
Synonyms : | CD70; CD70 molecule; CD27L; LPFS3; CD27-L; CD27LG; TNFSF7; TNLG8A; CD70 antigen; CD27 ligand; Ki-24 antigen; surface antigen CD70; tumor necrosis factor ligand 8A; tumor necrosis factor ligand superfamily member 7 |
Gene ID : | 970 |
mRNA Refseq : | NM_001252 |
Protein Refseq : | NP_001243 |
MIM : | 602840 |
UniProt ID : | P32970 |
Products Types
◆ Lysates | ||
CD70-2710HCL | Recombinant Human CD70 cell lysate | +Inquiry |
CD70-1303RCL | Recombinant Rat CD70 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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