Recombinant Human CD80 Protein, C-His-tagged
Cat.No. : | CD80-185H |
Product Overview : | Recombinant Human CD80 Protein with C-His tag was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
Description : | CD80 (B7-1, BB1) and CD86 (B7-2, B70) are members of the B7 family of cell surface ligands that regulate T cell activation and immune responses. CD80 is expressed on activated antigen presenting cells, including dendritic cells, B cells, monocytes, and macrophages. CD86 is expressed on resting monocytes, dendritic cells, activated B lymphocytes, and can be further upregulated in the presence of inflammation. CD80 and CD86 are ligands for CD28, which functions as a T cell costimulatory receptor. Interaction of CD28 with CD80 or CD86 provides the second signal required for naïve T cell activation, T cell proliferation, and acquisition of effector functions. Alternatively, CD80 and CD86 also act as ligands to CTLA-4, which results in the downregulation of T cell activity. |
Source : | E. coli |
Species : | Human |
Tag : | C-His |
Molecular Mass : | ~23 kDa |
AA Sequence : | VIHVTKEVKEVATLSCGHNVSVEEL AQTRIYWQKEKKMVLTMMSGDMNIW PEYKNRTIFDITNNLSIVILALRPS DEGTYECVVLKYEKDAFKREHLAEV TLSVKADFPTPSISDFEIPTSNIRR IICSTSGGFPEPHLSWLENGEELNA INTTVSQDPETELYAVSSKLDFNMT TNHSFMCLIKYGHLRVNQTFNWNTT KQEHFPDN |
Purity : | Transferred into competent cells and the supernatant was purified by NI column affinity chromatography and the purity is > 85% (by SDS-PAGE). |
Notes : | For research use only, not for use in diagnostic procedure. |
Storage : | Store at 4 centigrade short term. Aliquot and store at -20 centigrade long term. Avoid freeze-thaw cycles. |
Concentration : | ≥0.5 mg/mL |
Storage Buffer : | PBS, 4M Urea, pH7.4 |
Gene Name : | CD80 CD80 molecule [ Homo sapiens (human) ] |
Official Symbol : | CD80 |
Synonyms : | CD80; CD80 molecule; CD28LG, CD28LG1, CD80 antigen (CD28 antigen ligand 1, B7 1 antigen) , CD80 molecule; T-lymphocyte activation antigen CD80; B lymphocyte activation antigen B7; B7 1; B7.1; activation B7-1 antigen; costimulatory factor CD80; CTLA-4 counter-receptor B7.1; B-lymphocyte activation antigen B7; costimulatory molecule variant IgV-CD80; CD80 antigen (CD28 antigen ligand 1, B7-1 antigen); B7; BB1; B7-1; LAB7; CD28LG; CD28LG1; |
Gene ID : | 941 |
mRNA Refseq : | NM_005191 |
Protein Refseq : | NP_005182 |
MIM : | 112203 |
UniProt ID : | P33681 |
Products Types
◆ Recombinant Protein | ||
Cd80-5171M | Active Recombinant Mouse Cd80 protein(Met1-Lys245), His-tagged | +Inquiry |
Cd80-1271R | Recombinant Rat Cd80 Protein, His-tagged | +Inquiry |
CD80-586C | Recombinant Cynomolgus monkey CD80 Protein | +Inquiry |
CD80-1347M | Acitve Recombinant Mouse CD80 protein(Met1-Lys245), hFc-tagged | +Inquiry |
CD80-0864H | Recombinant Human CD80 Protein, GST-Tagged | +Inquiry |
◆ Lysates | ||
CD80-2715HCL | Recombinant Human CD80 cell lysate | +Inquiry |
CD80-1767MCL | Recombinant Mouse CD80 cell lysate | +Inquiry |
CD80-948CCL | Recombinant Cynomolgus CD80 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket