Recombinant Human CD86 protein, His-Avi-tagged

• Cat.No.: CD86-580H
• Product Overview: Recombinant human CD86/B7-2 Protein is expressed from mammalian with a His and Avi tag at the C-terminal. It contains Leu26-Pro247.

Specification

• Description: Human B7-H2, also called B7RP-1, B7h, LICOS, and GL50, is a member of the growing B7 family of immune costimulatory proteins. Other family members include B7-1, B7-2, B7-H1(PD-L1), PD-L2, and B7-H3. B7 proteins are members of the immunoglobulin(Ig) superfamily, the extracellular domains contain 2 Ig-like domains and all members have short cytoplasmic domains. Among the family members, they share about 20-25% amino acid identity. Human and mouse B7-H2 share approximately 49% amino acid identity.
• Source: HEK293
• Species: Human
• Tag: His-Avi
• Form: Supplied as 0.22μm filtered solution in PBS (pH 7.4).
• Molecular Mass: The protein has a predicted MW of 28.2 kDa. Due to glycosylation, the protein migrates to 55-70 kDa based on Bis-Tris PAGE result.
• Protein length: Leu26-Pro247
• Endotoxin: Less than 0.05 EU per μg by the LAL method.
• Purity: >95% as determined by Bis-Tris PAGE; >95% as determined by HPLC
• Storage: The product should be stored at -70°C. Please do not repeated freeze-thaw cycles.

Gene Information

• Gene Name: CD86
• Official Symbol: CD86
• Synonyms: CD86 antigen; CD86 molecule; CD86; B70; B7-2 antigen; B72; B7-2; Activation B7-2 antigen; B-lymphocyte activation antigen B7-2; BU63; CD28 antigen ligand 2; CD28LG2B7-2 antigen); CTLA-4 counter-receptor B7.2; FUN-1; LAB72; MGC34413; T-lymphocyte activation antigen CD86
• Gene ID: 942
• mRNA Refseq: NM_001206924.1
• Protein Refseq: NP_001193853.1
• MIM: 601020
• UniProt ID: P42081