Recombinant Human CD9 protein, His-tagged
Cat.No. : | CD9-3867H |
Product Overview : | Recombinant Human CD9 (Ser112-Ile195) protein was fused to His-tag at C-terminus and expressed in human 293 cells (HEK293). |
Availability | February 16, 2025 |
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Description : | CD9 antigen is also known as tetraspanin-29 (TSPAN29), 5H9 antigen, Leukocyte antigen MIC3 (MIC3), Motility-related protein, is a multi-pass membrane protein which belongs to the tetraspanin (TM4SF) family or the transmembrane 4 superfamily. CD9 is a cell surface glycoprotein that is known to complex with integrins and other transmembrane 4 superfamily proteins. TSPAN29 is found on the surface of exosomes. MIC3 Involved in platelet activation and aggregation, regulates paranodal junction formation and also Involved in cell adhesion, cell motility and tumor metastasis. CD9 antigen also seems to be a key part in the egg-sperm fusion during mammalian fertilization. |
Source : | HEK293 |
Species : | Human |
Tag : | His |
Predicted N Terminal : | Ser112 |
Form : | Lyophilized from 0.22 μm filtered solution in PBS, pH7.4, 10% trehalose. |
Molecular Mass : | The protein has a calculated MW of 11.6 kDa. The protein migrates as 12 kDa under reducing (R) condition (SDS-PAGE). |
Protein length : | Ser112-Ile195 |
Endotoxin : | Less than 1.0 EU per μg by the LAL method. |
Purity : | >95% as determined by SDS-PAGE. |
Storage : | For long term storage, the product should be stored at lyophilized state at -20 centigrade or lower. Please avoid repeated freeze-thaw cycles. This product is stable after storage at: -20 to -70 centigrade for 12 months in lyophilized state; -70 centigrade for 3 months under sterile conditions after reconstitution. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents. |
Gene Name : | CD9 |
Official Symbol : | CD9 |
Synonyms : | CD9; CD9 molecule; CD9 antigen (p24) , MIC3; CD9 antigen; BA2; motility related protein 1; MRP 1; P24; TSPAN29; 5H9 antigen; tetraspanin-29; BA-2/p24 antigen; CD9 antigen (p24); leukocyte antigen MIC3; motility related protein-1; cell growth-inhibiting gene 2 protein; MIC3; MRP-1; BTCC-1; DRAP-27; TSPAN-29; FLJ99568 |
Gene ID : | 928 |
mRNA Refseq : | NM_001769 |
Protein Refseq : | NP_001760 |
MIM : | 143030 |
UniProt ID : | P21926 |
Products Types
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CD9-3104H | Recombinant Human CD9 Protein, MYC/DDK-tagged | +Inquiry |
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◆ Lysates | ||
CD9-2110HCL | Recombinant Human CD9 cell lysate | +Inquiry |
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Not For Human Consumption!
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Customer Reviews (3)
Write a reviewIts unique characteristics contribute to obtaining clear and detailed structural information, allowing researchers to gain insights into protein interactions and conformational changes.
The CD9 protein comes highly recommended for its exceptional performance in various research applications.
Its exceptional purity and stability make it an ideal choice for a wide range of applications, ensuring reliable and reproducible results.
Q&As (5)
Ask a questionStudies have suggested that CD9 protein expression levels may be associated with chemoresistance in certain types of cancer, making it a potential predictive marker for chemotherapy response.
Studies have suggested that changes in CD9 protein expression in renal cells may be associated with the progression of chronic kidney disease, making it a potential biomarker for monitoring disease progression.
As of now, there are no FDA-approved diagnostic tests or therapies specifically targeting CD9 protein, but ongoing research may lead to future applications.
CD9 protein expression has been associated with cardiovascular diseases such as atherosclerosis and thrombosis, and its levels are being studied as a potential prognostic marker for these conditions.
CD9 protein is involved in the regulation of mast cell activation and degranulation, processes that are central to the development of asthma and allergic reactions.
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