Recombinant Human CD9 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: CD9-2958H
• Product Overview: CD9 MS Standard C13 and N15-labeled recombinant protein (NP_001760) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Tetraspanins are cell surface glycoproteins with four transmembrane domains that form multimeric complexes with other cell surface proteins. The encoded protein functions in many cellular processes including differentiation, adhesion, and signal transduction, and expression of this gene plays a critical role in the suppression of cancer cell motility and metastasis.
• Source: HEK293
• Species: Human
• Tag: Myc&DDK
• Molecular Mass: 25.4 kDa
• AA Sequence: MPVKGGTKCIKYLLFGFNFIFWLAG IAVLAIGLWLRFDSQTKSIFEQETN NNNSSFYTGVYILIGAGALMMLVGF LGCCGAVQESQCMLGLFFGFLLVIF AIEIAAAIWGYSHKDEVIKEVQEFY KDTYNKLKTKDEPQRETLKAIHYAL NCCGLAGGVEQFISDICPKKDVLET FTVKSCPDAIKEVFDNKFHIIGAVG IGIAVVMIFGMIFSTILCCAIRRNR EMVTRTRPLEQKLISEEDLAANDIL DYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: CD9 CD9 molecule [ Homo sapiens (human) ]
• Official Symbol: CD9
• Synonyms: CD9; CD9 molecule; CD9 antigen (p24), MIC3; CD9 antigen; BA2; motility related protein 1; MRP 1; P24; TSPAN29; 5H9 antigen; tetraspanin-29; BA-2/p24 antigen; CD9 antigen (p24); leukocyte antigen MIC3; motility related protein-1; cell growth-inhibiting gene 2 protein; MIC3; MRP-1; BTCC-1; DRAP-27; TSPAN-29; FLJ99568
• Gene ID: 928
• mRNA Refseq: NM_001769
• Protein Refseq: NP_001760
• MIM: 143030
• UniProt ID: P21926

Reviews

10/14/2021

Its unique characteristics contribute to obtaining clear and detailed structural information, allowing researchers to gain insights into protein interactions and conformational changes.

06/21/2019

The CD9 protein comes highly recommended for its exceptional performance in various research applications.

09/08/2018

Its exceptional purity and stability make it an ideal choice for a wide range of applications, ensuring reliable and reproducible results.

Q&As

Can CD9 protein levels be used to predict the response to chemotherapy in cancer patients?

Studies have suggested that CD9 protein expression levels may be associated with chemoresistance in certain types of cancer, making it a potential predictive marker for chemotherapy response.

Can CD9 protein levels be used to monitor the progression of chronic kidney disease?

Studies have suggested that changes in CD9 protein expression in renal cells may be associated with the progression of chronic kidney disease, making it a potential biomarker for monitoring disease progression.

Are there any FDA-approved diagnostic tests or therapies targeting CD9 protein?

As of now, there are no FDA-approved diagnostic tests or therapies specifically targeting CD9 protein, but ongoing research may lead to future applications.

How does CD9 protein expression correlate with prognosis in cardiovascular diseases?

CD9 protein expression has been associated with cardiovascular diseases such as atherosclerosis and thrombosis, and its levels are being studied as a potential prognostic marker for these conditions.

How does CD9 protein contribute to the pathogenesis of asthma and allergic reactions?

CD9 protein is involved in the regulation of mast cell activation and degranulation, processes that are central to the development of asthma and allergic reactions.