Recombinant Human CDH8 Protein, Myc/DDK-tagged, C13 and N15-labeled

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Recombinant Human CDH8 Protein, Myc/DDK-tagged, C13 and N15-labeled

CDH8 Related Products

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Cat.No. : CDH8-4940H
Product Overview : CDH8 MS Standard C13 and N15-labeled recombinant protein (NP_001787) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
Description : This gene encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. The extracellular domain consists of 5 subdomains, each containing a cadherin motif, and appears to determine the specificity of the protein's homophilic cell adhesion activity. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. This particular cadherin is expressed in brain and is putatively involved in synaptic adhesion, axon outgrowth and guidance.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 88.25 kDa
AA Sequence : MPERLAEMLL DLWTPLIILW ITLPPCIYMA PMNQSQVLMS GSPLELNSLG EEQRILNRSK RGWVWNQMFV LEEFSGPEPI LVGRLHTDLD PGSKKIKYIL SGDGAGTIFQ INDVTGDIHA IKRLDREEKA EYTLTAQAVD WETSKPLEPP SEFIIKVQDI NDNAPEFLNG PYHATVPEMS ILGTSVTNVT ATDADDPVYG NSAKLVYSIL EGQPYFSIEP ETAIIKTALP NMDREAKEEY LVVIQAKDMG GHSGGLSGTT TLTVTLTDVN DNPPKFAQSL YHFSVPEDVV LGTAIGRVKA NDQDIGENAQ SSYDIIDGDG TALFEITSDA QAQDGIIRLR KPLDFETKKS YTLKVEAANV HIDPRFSGRG PFKDTATVKI VVEDADEPPV FSSPTYLLEV HENAALNSVI GQVTARDPDI TSSPIRFSID RHTDLERQFN INADDGKITL ATPLDRELSV WHNITIIATE IRNHSQISRV PVAIKVLDVN DNAPEFASEY EAFLCENGKP GQVIQTVSAM DKDDPKNGHY FLYSLLPEMV NNPNFTIKKN EDNSLSILAK HNGFNRQKQE VYLLPIIISD SGNPPLSSTS TLTIRVCGCS NDGVVQSCNV EAYVLPIGLS MGALIAILAC IILLLVIVVL FVTLRRHKNE PLIIKDDEDV RENIIRYDDE GGGEEDTEAF DIATLQNPDG INGFLPRKDI KPDLQFMPRQ GLAPVPNGVD VDEFINVRLH EADNDPTAPP YDSIQIYGYE GRGSVAGSLS SLESTTSDSD QNFDYLSDWG PRFKRLGELY SVGESDKETT RTRPLEQKLI SEEDLAANDI LDYKDDDDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
SDS-PAGE :

Gene Name : CDH8 cadherin 8 [ Homo sapiens (human) ]
Official Symbol : CDH8
Synonyms : CDH8; cadherin 8, type 2; cadherin-8; Nbla04261;
Gene ID : 1006
mRNA Refseq : NM_001796
Protein Refseq : NP_001787
MIM : 603008
UniProt ID : P55286

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