Recombinant Human CDK8 Protein, GST-Tagged CDK8-1038H

Recombinant Human CDK8 Protein, GST-Tagged

PRODUCTS

Home / Products / Recombinant Human CDK8 Protein, GST-Tagged

Recombinant Human CDK8 Protein, GST-Tagged

CDK8 Related Products

Price Inquiry

Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.

Cat.No. : CDK8-1038H
Product Overview : Human CDK8 (NP_001251.1, 1 a.a. - 464 a.a.) and CCNC (NP_005181.2, 1 a.a. - 283 a.a.) full-length recombinant protein with with GST tag expressed in baculovirus infected Sf21 cells.
Description : This gene encodes a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are known to be important regulators of cell cycle progression. This kinase and its regulatory subunit, cyclin C, are components of the Mediator transcriptional regulatory complex, involved in both transcriptional activation and repression by phosphorylation of the carboxy-terminal domain of the largest subunit of RNA polymerase II. This kinase regulates transcription by targeting the cyclin-dependent kinase 7 subunits of the general transcription initiation factor IIH, thus providing a link between the Mediator complex and the basal transcription machinery. Multiple pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2016]
Source : Insect Cell
Species : Human
Tag : GST
Form : Liquid
Bio-activity : The activity was determined by ELISA. The enzyme was incubated with biotinylated substrate protein, and after stopping kinase reaction by EDTA, the reaction solution was transferred into streptavidin- coated plate. Phosphorylation was detected by anti-phospho antibody and HRP-labeled anti-rabbit IgG.
Substrate: RNA polymerase peptide. ATP: 100 μM.
Molecular Mass : 80 kDa
Purity : 91 % by SDS-PAGE/CBB staining
Applications : Functional Study
SDS-PAGE
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : In 50 mM Tris-HCl, 150 mM NaCl, pH 7.5 (0.1% CHAPS, 1 mM DTT, 10% glycerol)
Quality Control Testing :

Loading 1 μg protein in SDS-PAGE

Result of activity analysis :

Gene Name : CDK8 cyclin-dependent kinase 8 [ Homo sapiens ]
Official Symbol : CDK8
Synonyms : CDK8; cyclin-dependent kinase 8; K35; protein kinase K35; CDK8 protein kinase; mediator complex subunit CDK8; cell division protein kinase 8; mediator of RNA polymerase II transcription subunit CDK8; MGC126074; MGC126075;
Gene ID : 1024
mRNA Refseq : NM_001260
Protein Refseq : NP_001251
MIM : 603184
UniProt ID : P49336

Online Inquiry


  • Note: There will be extra charge for optional service!
  • Please input "biomart" as verification code. Please review Creative BioMart's privacy policy for more information

Optional Service: Optional requirements on this protein

Other Requirements:

Back to School Promotion

Apply For A Coupon

$50 OFF Your First Purchase

Apply For a Coupon

Enter your email here to subscribe.

creative biomart inc.

Easy access to products and services you need from our library via powerful searching tools.

Follow Us

Copyright © 2007 – 2020 Creative BioMart. All Rights Reserved. Terms and Conditions | Privacy Policy