| Description : |
This gene encodes a protein found in corneodesmosomes, which localize to human epidermis and other cornified squamous epithelia. The encoded protein undergoes a series of cleavages during corneocyte maturation. This gene is highly polymorphic in human populations, and variation has been associated with skin diseases such as psoriasis, hypotrichosis and peeling skin syndrome. The gene is located in the major histocompatibility complex (MHC) class I region on chromosome 6. |
| Source : |
E. coli |
| Species : |
Human |
| Tag : |
His & GST |
| Form : |
Freeze-dried powder |
| Molecular Mass : |
Predicted Molecular Mass: 59.5kDa |
| Protein length : |
Lys33~Gly300 (Accession # Q15517) |
| Endotoxin : |
<1.0EU per 1ug (determined by the LAL method) |
| Purity : |
>90% |
| Applications : |
SDS-PAGE; WB; ELISA; IP. |
| Stability : |
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition. |
| Storage : |
Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months. |
| Storage buffer : |
Supplied as lyophilized form in 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% sarcosyl, 5% trehalose, and preservative. |
| Reconstitution : |
Reconstitute in sterile ddH2O. |
| Isoelectric Point : |
7.8 |
