Recombinant Human CELF1 Protein, Myc/DDK-tagged, C13 and N15-labeled

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Recombinant Human CELF1 Protein, Myc/DDK-tagged, C13 and N15-labeled

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Cat.No. : CELF1-1244H
Product Overview : CELF1 MS Standard C13 and N15-labeled recombinant protein (NP_006551) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
Description : Members of the CELF/BRUNOL protein family contain two N-terminal RNA recognition motif (RRM) domains, one C-terminal RRM domain, and a divergent segment of 160-230 aa between the second and third RRM domains. Members of this protein family regulate pre-mRNA alternative splicing and may also be involved in mRNA editing, and translation. This gene may play a role in myotonic dystrophy type 1 (DM1) via interactions with the dystrophia myotonica-protein kinase (DMPK) gene. Alternative splicing results in multiple transcript variants encoding different isoforms.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 51.6 kDa
AA Sequence : MNGTLDHPDQ PDLDAIKMFV GQVPRTWSEK DLRELFEQYG AVYEINVLRD RSQNPPQSKG CCFVTFYTRK AALEAQNALH NMKVLPGMHH PIQMKPADSE KNNAVEDRKL FIGMISKKCT ENDIRVMFSS FGQIEECRIL RGPDGLSRGC AFVTFTTRAM AQTAIKAMHQ AQTMEGCSSP MVVKFADTQK DKEQKRMAQQ LQQQMQQISA ASVWGNLAGL NTLGPQYLAL LQQTASSGNL NTLSSLHPMG GLNAMQLQNL AALAAAASAA QNTPSGTNAL TTSSSPLSVL TSSAGSSPSS SSSNSVNPIA SLGALQTLAG ATAGLNVGSL AGMAALNGGL GSSGLSNGTG STMEALTQAY SGIQQYAAAA LPTLYNQNLL TQQSIGAAGS QKEGPEGANL FIYHLPQEFG DQDLLQMFMP FGNVVSAKVF IDKQTNLSKC FGFVSYDNPV SAQAAIQSMN GFQIGMKRLK VQLKRSKNDS KPYTRTRPLE QKLISEEDLA ANDILDYKDD DDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
SDS-PAGE :

Gene Name : CELF1 CUGBP Elav-like family member 1 [ Homo sapiens (human) ]
Official Symbol : CELF1
Synonyms : CELF1; CUGBP, Elav-like family member 1; CUG triplet repeat, RNA binding protein 1, CUG triplet repeat, RNA binding protein 1, CUGBP1; CUGBP Elav-like family member 1; bruno like 2; BRUNOL2; CUG RNA binding protein; CUG BP; CUGBP; EDEN BP; embryo deadenylation element binding protein; hNab50; NAB50; NAPOR; nuclear polyadenylated RNA binding protein; 50 kD; CELF-1; CUG-BP1; bruno-like 2; EDEN-BP homolog; bruno-like protein 2; CUG RNA-binding protein; deadenylation factor CUG-BP; RNA-binding protein BRUNOL-2; CUG-BP- and ETR-3-like factor 1; CUG triplet repeat RNA-binding protein 1; CUG triplet repeat, RNA binding protein 1; CUG triplet repeat, RNA-binding protein 1; 50 kDa nuclear polyadenylated RNA-binding protein; nuclear polyadenylated RNA-binding protein, 50-kD; embryo deadenylation element-binding protein homolog; CUG-BP; CUGBP1; EDEN-BP;
Gene ID : 10658
mRNA Refseq : NM_006560
Protein Refseq : NP_006551
MIM : 601074
UniProt ID : Q92879

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