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Recombinant Human CENPF Protein, His-tagged

Cat.No. : CENPF-486H
Product Overview : Recombinant Human CENPF(Gln436~Lys637) fused with His tag at N-terminal was expressed in E. coli.
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  • Gene Information
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Description : This gene encodes a protein that associates with the centromere-kinetochore complex. The protein is a component of the nuclear matrix during the G2 phase of interphase. In late G2 the protein associates with the kinetochore and maintains this association through early anaphase. It localizes to the spindle midzone and the intracellular bridge in late anaphase and telophase, respectively, and is thought to be subsequently degraded. The localization of this protein suggests that it may play a role in chromosome segregation during mitotis. It is thought to form either a homodimer or heterodimer. Autoantibodies against this protein have been found in patients with cancer or graft versus host disease.
Source : E. coli
Species : Human
Tag : His
Form : PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Molecular Mass : 27.7kDa
Identity : Reconstitute in PBS or others
Protein length : Gln436~Lys637
Endotoxin : <1.0EU per 1µg (determined by the LAL method)
Purity : > 95%
Applications : Positive Control; Immunogen; SDS-PAGE; WB.
If bio-activity of the protein is needed, please check active protein
Stability : The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage : Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
Reconstitution : Reconstitute in PBS or others
Gene Name : CENPF centromere protein F, 350/400kDa (mitosin) [ Homo sapiens ]
Official Symbol : CENPF
Synonyms : CENPF; centromere protein F, 350/400kDa (mitosin); centromere protein F (350/400kD, mitosin); centromere protein F; hcp 1; mitosin; AH antigen; kinetochore protein CENPF; CENP-F kinetochore protein; cell-cycle-dependent 350K nuclear protein; centromere protein F, 350/400ka (mitosin); CENF; hcp-1; PRO1779;
Gene ID : 1063
mRNA Refseq : NM_016343
Protein Refseq : NP_057427
MIM : 600236
UniProt ID : P49454

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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