Recombinant Human CFHR1 protein, GST-tagged

• Cat.No.: CFHR1-27138TH
• Product Overview: Recombinant Human CFHR1(19 a.a. - 330 a.a.) fused with GST tag at N-terminal was expressed in Wheat Germ.

Specification

• Description: This gene encodes a secreted protein belonging to the complement factor H protein family. It binds to Pseudomonas aeruginosa elongation factor Tuf together with plasminogen, which is proteolytically activated. It is proposed that Tuf acts as a virulence factor by acquiring host proteins to the pathogen surface, controlling complement, and facilitating tissue invasion. Mutations in this gene are associated with an increased risk of atypical hemolytic-uremic syndrome.
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Form: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
• Molecular Mass: 60.06 kDa
• AA Sequence: EATFCDFPKINHGILYDEEKYKPFS QVPTGEVFYYSCEYNFVSPSKSFWT RITCTEEGWSPTPKCLRLCFFPFVE NGHSESSGQTHLEGDTVQIICNTGY RLQNNENNISCVERGWSTPPKCRST DTSCVNPPTVQNAHILSRQMSKYPS GERVRYECRSPYEMFGDEEVMCLNG NWTEPPQCKDSTGKCGPPPPIDNGD ITSFPLSVYAPASSVEYQCQNLYQL EGNKRITCRNGQWSEPPKCLHPCVI SREIMENYNIALRWTAKQKLYLRTG ESAEFVCKRGYRLSSRSHTLRTTCW DGKLEYPTCAKR
• Applications: Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Protein length: 19-330

Gene Information

• Gene Name: CFHR1 complement factor H-related 1 [ Homo sapiens ]
• Official Symbol: CFHR1
• Synonyms: CFHR1; complement factor H-related 1; CFHL1, CFHL1P, CFHR1P, complement factor H related 1 pseudogene , H factor (complement) like 1 , H factor (complement) like 2 , HFL1, HFL2; complement factor H-related protein 1; CFHL; FHR1; H36 1; H36 2; H36; FHR-1; H-factor-like 1; h factor-like protein 1; H factor (complement)-like 1; H factor (complement)-like 2; complement factor H-related 1 pseudogene; HFL1; HFL2; CFHL1; H36-1; H36-2; CFHL1P; CFHR1P; MGC104329
• Gene ID: 3078
• mRNA Refseq: NM_002113
• Protein Refseq: NP_002104
• MIM: 134371
• UniProt ID: Q03591
• Chromosome Location: 1q32