Recombinant Human CHAC1 Protein, GST-Tagged

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Recombinant Human CHAC1 Protein, GST-Tagged

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Cat.No. : CHAC1-1199H
Product Overview : Human CHAC1 full-length ORF (NP_077016.1, 1 a.a. - 222 a.a.) recombinant protein with GST tag at N-terminal.
Description : This gene encodes a member of the gamma-glutamylcyclotransferase family of proteins. The encoded protein has been shown to promote neuronal differentiation by deglycination of the Notch receptor, which prevents receptor maturation and inhibits Notch signaling. This protein may also play a role in the unfolded protein response, and in regulation of glutathione levels and oxidative balance in the cell. Elevated expression of this gene may indicate increased risk of cancer recurrence among breast and ovarian cancer patients. [provided by RefSeq, Sep 2016]
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 50.8 kDa
AA Sequence : MKQESAAPNT PPTSQSPTPS AQFPRNDGDP QALWIFGYGS LVWRPDFAYS DSRVGFVRGY SRRFWQGDTF HRGSDKMPGR VVTLLEDHEG CTWGVAYQVQ GEQVSKALKY LNVREAVLGG YDTKEVTFYP QDAPDQPLKA LAYVATPQNP GYLGPAPEEA IATQILACRG FSGHNLEYLL RLADFMQLCG PQAQDEHLAA IVDAVGTMLP CFCPTEQALA LV
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Quality Control Testing :

12.5% SDS-PAGE Stained with Coomassie Blue

Gene Name : CHAC1 ChaC glutathione specific gamma-glutamylcyclotransferase 1 [ Homo sapiens (human) ]
Official Symbol : CHAC1
Synonyms : CHAC1; ChaC glutathione specific gamma-glutamylcyclotransferase 1; ChaC Glutathione Specific Gamma-Glutamylcyclotransferase 1; Gamma-GCT Acting On Glutathione Homolog 1; Blocks Notch Protein; Gamma-GCG 1; Botch; Glutathione-Specific Gamma-Glutamylcyclotransferase 1; ChaC, Cation Transport Regulator Homolog 1 (E. Coli); ChaC, Cation Transport Regulator Homolog 1; Cation Transport Regulator-Like Protein 1; ChaC, Cation Transport Regulator-Like 1; EC 2.3.2.-
Gene ID : 79094
mRNA Refseq : NM_024111
Protein Refseq : NP_077016
MIM : 614587
UniProt ID : Q9BUX1

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