Recombinant Human CHD1L Protein (704-897 aa), His-SUMO-tagged
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Cat.No. : | CHD1L-2043H |
Product Overview : | Recombinant Human CHD1L Protein (704-897 aa) is produced by E. coli expression system. This protein is fused with a 6xHis-SUMO tag at the N-terminal. Research Area: Epigenetics and Nuclear Signaling. Protein Description: Partial. |
Description : | DNA helicase which plays a role in chromatin-remodeling following DNA damage. Targeted to sites of DNA damage through interaction with poly(ADP-ribose) and functions to regulate chromatin during DNA repair. Able to catalyze nucleosome sliding in an ATP-dependent manner. Helicase activity is strongly stimulated upon poly(ADP-ribose)-binding. |
Source : | E. coli |
Species : | Human |
Tag : | His-SUMO |
Form : | Tris-based buffer,50% glycerol |
Molecular Mass : | 37.3 kDa |
Protein length : | 704-897 aa |
AA Sequence : | SAELDYQDPD ATSLKYVSGD VTHPQAGAED ALIVHCVDDS GHWGRGGLFT ALEKRSAEPR KIYELAGKMK DLSLGGVLLF PVDDKESRNK GQDLLALIVA QHRDRSNVLS GIKMAALEEG LKKIFLAAKK KKASVHLPRI GHATKGFNWY GTERLIRKHL AARGIPTYIY YFPRSKSAVL HAQSSSSSSR QLVP |
Purity : | > 90% as determined by SDS-PAGE. |
Notes : | Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week. |
Storage : | The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade. |
Concentration : | A hardcopy of COA with reconstitution instruction is sent along with the products. |
Figure : |
![]() (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel. |
Gene Name : | CHD1L chromodomain helicase DNA binding protein 1-like [ Homo sapiens ] |
Official Symbol : | CHD1L |
Synonyms : | ALC1; CHDL; |
Gene ID : | 9557 |
mRNA Refseq : | NM_024568.2 |
Protein Refseq : | NP_078844.2 |
MIM : | 613039 |
UniProt ID : | Q86WJ1 |
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