Recombinant Human CHD1L Protein (704-897 aa), His-SUMO-tagged

• Cat.No.: CHD1L-2043H
• Product Overview: Recombinant Human CHD1L Protein (704-897 aa) is produced by E. coli expression system. This protein is fused with a 6xHis-SUMO tag at the N-terminal. Research Area: Epigenetics and Nuclear Signaling. Protein Description: Partial.

Specification

• Description: DNA helicase which plays a role in chromatin-remodeling following DNA damage. Targeted to sites of DNA damage through interaction with poly(ADP-ribose) and functions to regulate chromatin during DNA repair. Able to catalyze nucleosome sliding in an ATP-dependent manner. Helicase activity is strongly stimulated upon poly(ADP-ribose)-binding.
• Source: E. coli
• Species: Human
• Tag: His-SUMO
• Form: Tris-based buffer,50% glycerol
• Molecular Mass: 37.3 kDa
• Protein length: 704-897 aa
• AA Sequence: SAELDYQDPDATSLKYVSGDVTHPQ AGAEDALIVHCVDDSGHWGRGGLFT ALEKRSAEPRKIYELAGKMKDLSLG GVLLFPVDDKESRNKGQDLLALIVA QHRDRSNVLSGIKMAALEEGLKKIF LAAKKKKASVHLPRIGHATKGFNWY GTERLIRKHLAARGIPTYIYYFPRS KSAVLHAQSSSSSSRQLVP
• Purity: > 90% as determined by SDS-PAGE.
• Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week.
• Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade.
• Concentration: A hardcopy of COA with reconstitution instruction is sent along with the products.

Gene Information

• Gene Name: CHD1L chromodomain helicase DNA binding protein 1-like [ Homo sapiens ]
• Official Symbol: CHD1L
• Synonyms: ALC1; CHDL
• Gene ID: 9557
• mRNA Refseq: NM_024568.2
• Protein Refseq: NP_078844.2
• MIM: 613039
• UniProt ID: Q86WJ1