Recombinant Human Chemokine (C-C motif) Ligand 3
Cat.No. : | CCL3-363H |
Product Overview : | Recombinant humanCCL3 contains 69 amino acid residues was expessed in Inscet cells. Itsmolecular weight is 7700 Dalton. |
- Specification
- Gene Information
- Related Products
Cat. No. : | CCL3-363H |
Description : | CCL3 is identical toMIP1-beta (ACT II isotype) except for two amino acid substitutions: argininefor histidine at position 22 and serine for glycine at position 47 of themature protein. |
Source : | Insect cells |
Species : | Human |
Form : | Lyophilized withoutadditives |
Molecular Weight : | 7.7 kDa |
Purity : | > 98% asdetermined by SDS-PAGE analysis |
Endotoxin Level : | < 0.1 ng/µg ofLAG1 |
Biological Activity : | Determined by itsability to chemoattract CCR5 transfected cells using a concentration of0.1-10.0 ng/ml. |
Reconstitution : | Centrifugevial prior to opening. First add sterile distilled water to the vial to fullysolubilize the protein to a concentration of 0.1-1.0 mg/ml. After completesolubilization of the protein, it can be further diluted to other aqueoussolutions. |
Storage : | Store lyophilizedprotein at -20°C to -80°C and reconstituted protein in working aliquots at-20°C to -80°C. Avoid repeated freeze-thaw cycles. |
OfficialSymbol : | CCL3 |
Gene Name : | CCL3 chemokine (C-C motif) ligand 22 [Homo sapiens ] |
Synonyms : | CCL3; chemokine (C-Cmotif) ligand 3; MIP1A; SCYA3; G0S19-1; LD78ALPHA; MIP-1-alpha; LD78 alphabeta; small inducible cytokine A3 (homologous to mouse Mip-1a); SIS-beta;G0/G1 switch regulatory protein 19-1; G0S19-1 protein; LD78 alpha beta;Macrophage inflammatory protein 1-alpha; PAT 464.1; Small-inducible cytokineA3; Tonsillar lymphocyte LD78 alpha protein; C-C motif chemokine 3;Small-inducible cytokine A3; MIP-1-alpha; Tonsillar lymphocyte LD78 alphaprotein; G0/G1 switch regulatory protein 19-1; G0S19-1 protein; SIS-beta; PAT464.1 |
Gene ID : | 6348 |
mRNA Refseq : | NM_002983 |
Protein Refseq : | NP_002974 |
MIM : | 182283 |
UniProt ID : | P10147 |
Chromosome Location : | 17q11-q21 |
Pathway : | Chemokine signalingpathway; Cytokine-cytokine receptor interaction; Chagas disease (Americantrypanosomiasis); Chemokine receptors bind chemokines; Class A/1(Rhodopsin-like receptors); GPCR ligand binding; IL12-mediated signalingevents; Peptide ligand-binding receptors; Rheumatoid arthritis; Senescenceand Autophagy; Salmonella infection; Signal Transduction; Signaling by GPCR;Toll-like receptor signaling pathway |
Function : | chemoattractantactivity; chemokine activity; signal transducer activity |
Products Types
◆ Recombinant Protein | ||
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CCL3-871R | Recombinant Rat CCL3 Protein, His (Fc)-Avi-tagged | +Inquiry |
CCL3-22H | Recombinant Human CCL3 Protein | +Inquiry |
◆ Lysates | ||
CCL3-7723HCL | Recombinant Human CCL3 293 Cell Lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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