CCL3-169H
Optional Service: Optional requirements on this protein
Product Overview :
Recombinant human CCL3 protein, fused to His-tag at N-terminus, was expressed in E.coli and purifed by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer(24-92aa).
Description :
CCL3, also known as, macrophage inflammatory protein-1alpha (MIP-1alpha), is a cytokine belonging to the CC chemokine family that is involved in the acute inflammatory state in the recruitment and activation of polymorphonuclear leukocytes. This protein has been identified as one of the major HIV-SFs produced by CD8+ T cells, along with MIP-1beta and RANTES. It acts as an inhibitor of different strains of HIV-1, HIV-2 and SIV infection in a dose-dependent manner.
Form :
Liquid. In 10mM Sodium Citrate ( pH3.5) containing 10% glycerol
Molecular Weight :
10.0 kDa (90aa), confirmed by MALDI-TOF(Molecular weight on SDS-PAGE will appear higher)
Purity :
> 90% by SDS - PAGE
Concentration :
0.25 mg/ml (determined by Bradford assay)
Endotoxin Level :
< 1.0 EU per 1 μg of protein (determined by LAL method )
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.