Recombinant Human CHP2 Protein, GST-Tagged

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Recombinant Human CHP2 Protein, GST-Tagged

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Cat.No. : CHP2-1262H
Product Overview : Human CHP2 full-length ORF (BAG35891.1, 1 a.a. - 196 a.a.) recombinant protein with GST-tag at N-terminal.
Description : This gene product is a small calcium-binding protein that regulates cell pH by controlling plasma membrane-type Na+/H+ exchange activity. This protein shares sequence similarity with calcineurin B and can bind to and stimulate the protein phosphatase activity of calcineurin A (CnA) and functions in the calcineurin/NFAT (nuclear factor of activated T cells) signaling pathway. Another member of the CHP subfamily, Calcineurin B homologous protein 1, is located on Chromosome 15 and is an inhibitor of calcineurin activity and has a genetic phenotype associated with Parkinson's Disease (OMIM:606988). This gene was initially identified as a tumor-associated antigen and was previously referred to as Hepatocellular carcinoma-associated antigen 520. [provided by RefSeq, Jul 2013]
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 47.96 kDa
AA Sequence : MGSRSSHAAV IPDGDSIRRE TGFSQASLLR LHHRFRALDR NKKGYLSRMD LQQIGALAVN PLGDRIIESF FPDGSQRVDF PGFVRVLAHF RPVEDEDTET QDPKKPEPLN SRRNKLHYAF QLYDLDRDGK ISRHEMLQVL RLMVGVQVTE EQLENIADRT VQEADEDGDG AVSFVEFTKS LEKMDVEQKM SIRILK
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene Name : CHP2 calcineurin B homologous protein 2 [ Homo sapiens ]
Official Symbol : CHP2
Synonyms : CHP2; calcineurin B homologous protein 2; hepatocellular carcinoma antigen gene 520; hepatocellular carcinoma-associated antigen 520;
Gene ID : 63928
mRNA Refseq : NM_022097
Protein Refseq : NP_071380

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Related Gene

CHPchp1CHP2

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