Recombinant Human CHRM4 Protein

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Recombinant Human CHRM4 Protein

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Cat.No. : CHRM4-1274H
Product Overview : Human CHRM4 full-length ORF (NP_000732.2) recombinant protein without tag.
Description : The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The clinical implications of this receptor are unknown; however, mouse studies link its function to adenylyl cyclase inhibition. [provided by RefSeq, Jul 2008]
Source : Wheat Germ
Species : Human
Form : Liquid
Molecular Mass : 53 kDa
AA Sequence : MANFTPVNGS SGNQSVRLVT SSSHNRYETV EMVFIATVTG SLSLVTVVGN ILVMLSIKVN RQLQTVNNYF LFSLACADLI IGAFSMNLYT VYIIKGYWPL GAVVCDLWLA LDYVVSNASV MNLLIISFDR YFCVTKPLTY PARRTTKMAG LMIAAAWVLS FVLWAPAILF WQFVVGKRTV PDNQCFIQFL SNPAVTFGTA IAAFYLPVVI MTVLYIHISL ASRSRVHKHR PEGPKEKKAK TLAFLKSPLM KQSVKKPPPG EAAREELRNG KLEEAPPPAL PPPPRPVADK DTSNESSSGS ATQNTKERPA TELSTTEATT PAMPAPPLQP RALNPASRWS KIQIVTKQTG NECVTAIEIV PATPAGMRPA ANVARKFASI ARNQVRKKRQ MAARERKVTR TIFAILLAFI LTWTPYNVMV LVNTFCQSCI PDTVWSIGYW LCYVNSTINP ACYALCNATF KKTFRHLLLC QYRNIGTAR
Applications : Antibody Production
Functional Study
Compound Screening
Usage : Heating may cause protein aggregation. Please do not heat this product before electrophoresis.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 25 mM Tris-HCl of pH8.0 containing 2% glycerol.
Gene Name : CHRM4 cholinergic receptor, muscarinic 4 [ Homo sapiens ]
Official Symbol : CHRM4
Synonyms : CHRM4; cholinergic receptor, muscarinic 4; muscarinic acetylcholine receptor M4; acetylcholine receptor; muscarinic 4; acetylcholine receptor, muscarinic 4; HM4; M4R;
Gene ID : 1132
mRNA Refseq : NM_000741
Protein Refseq : NP_000732
MIM : 118495
UniProt ID : P08173

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