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Recombinant Human CHRNA3 Protein, GST-Tagged

Cat.No. : CHRNA3-1280H
Product Overview : Human CHRNA3 full-length ORF (AAH06114.1, 1 a.a. - 489 a.a.) recombinant protein with GST-tag at N-terminal.
  • Specification
  • Gene Information
  • Related Products
Description : This locus encodes a member of the nicotinic acetylcholine receptor family of proteins. Members of this family of proteins form pentameric complexes comprised of both alpha and beta subunits. This locus encodes an alpha-type subunit, as it contains characteristic adjacent cysteine residues. The encoded protein is a ligand-gated ion channel that likely plays a role in neurotransmission. Polymorphisms in this gene have been associated with an increased risk of smoking initiation and an increased susceptibility to lung cancer. Alternatively spliced transcript variants have been described. [provided by RefSeq, Nov 2009]
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 79.42 kDa
AA Sequence : MGSGPLSLPLALSPPRLLLLLLLSL LPVARASEAEHRLFERLFEDYNEII RPVANVSDPVIIHFEVSMSQLVKVD EVNQIMETNLWLKQIWNDYKLKWNP SDYGGAEFMRVPAQKIWKPDIVLYN NAVGDFQVDDKTKALLKYTGEVTWI PPAIFKSSCKIDVTYFPFDYQNCTM KFGSWSYDKAKIDLVLIGSSMNLKD YWESGEWAIIKAPGYKHDIKYNCCE EIYPDITYSLYIRRLPLFYTINLII PCLLISFLTVLVFYLPSDCGEKVTL CISVLLSLTVFLLVITETIPSTSLV IPLIGEYLLFTMIFVTLSIVITVFV LNVHYRTPTTHTMPSWVKTVFLNLL PRVMFMTRPTSNEGNAQKPRPLYGA ELSNLNCFSRAESKGCKEGYPCQDG MCGYCHHRRIKISNFSANLTRSSSS ESVDAVLSLSALSPEIKEAIQSVKY IAENMKAQNEAKEEQKAQEIQQLKR KEKSTETSDQEPGL
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene Name : CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal) [ Homo sapiens ]
Official Symbol : CHRNA3
Synonyms : CHRNA3; cholinergic receptor, nicotinic, alpha 3 (neuronal); cholinergic receptor, nicotinic, alpha polypeptide 3; neuronal acetylcholine receptor subunit alpha-3; acetylcholine receptor; nicotinic; alpha 3 (neuronal); neuronal nicotinic acetylcholine receptor, alpha3 subunit; LNCR2; PAOD2; NACHRA3; MGC104879;
Gene ID : 1136
mRNA Refseq : NM_000743
Protein Refseq : NP_000734
MIM : 118503
UniProt ID : P32297

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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