Recombinant Human CHST15 Protein, GST-tagged

• Cat.No.: CHST15-4686H
• Product Overview: Human GALNAC4S-6ST full-length ORF ( AAH27908, 1 a.a. - 561 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: Chondroitin sulfate (CS) is a glycosaminoglycan which is an important structural component of the extracellular matrix and which links to proteins to form proteoglycans. Chondroitin sulfate E (CS-E) is an isomer of chondroitin sulfate in which the C-4 and C-6 hydroxyl groups are sulfated. This gene encodes a type II transmembrane glycoprotein that acts as a sulfotransferase to transfer sulfate to the C-6 hydroxal group of chondroitin sulfate. This gene has also been identified as being co-expressed with RAG1 in B-cells and as potentially acting as a B-cell surface signaling receptor. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2012]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 87.45 kDa
• AA Sequence: MRHCINCCIQLLPDGAHKQQVNCQG GPHHGHQACPTCKGENKILFRVDSK QMNLLAVLEVRTEGNENWGGFLRFK KGKRCSLVFGLIIMTLVMASYILSG AHQELLISSPFHYGGFPSNPSLMDS ENPSDTKEHHHQSSVNNISYMKDYP SIKLIINSITTRIEFTTRQLPDLED LKKQELHMFSVIPNKFLPNSKSPCW YEEFSGQNTTDPYLTNSYVLYSKRF RSTFDALRKAFWGHLAHAHGKHFRL RCLPHFYIIGQPKCGTTDLYDRLRL HPEVKFSAIKEPHWWTRKRFGIVRL RDGLRDRYPVEDYLDLFDLAAHQIH QGLQASSAKEQSKMNTIIIGEASAS TMWDNNAWTFFYDNSTDGEPPFLTQ DFIHAFQPNARLIVMLRDPVERLYS DYLYFASSNKSADDFHEKVTEALQL FENCMLDYSLRACVYNNTLNNAMPV RLQVGLYAVYLLDWLSVFDKQQFLI LRLEDHASNVKYTMHKVFQFLNLGP LSEKQEALMTKSPASNARRPEDRNL GPMWPITQKILRDFYRPFNARLAQV LADEAFAWKTT
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: CHST15 carbohydrate sulfotransferase 15 [ Homo sapiens (human) ]
• Official Symbol: CHST15
• Synonyms: CHST15; carbohydrate sulfotransferase 15; BRAG; GALNAC4S-6ST; carbohydrate sulfotransferase 15; B cell RAG associated protein (GALNAC4S-6ST); B-cell RAG-associated gene protein; carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15; hBRAG; EC 2.8.2.33
• Gene ID: 51363
• mRNA Refseq: NM_001270764
• Protein Refseq: NP_001257693
• MIM: 608277
• UniProt ID: Q7LFX5