Recombinant Human CHSY3, His-tagged

• Cat.No.: CHSY3-11236H
• Product Overview: Recombinant Human CHSY3 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.

Specification

• Description: CSS3 is a glycosyltransferase that has both glucuronyltransferase and N-acetylgalactosaminyltransferase activities (Yada et al., 2003 [PubMed 12907687]).
• Source: E.coli
• Species: Human
• Tag: His
• Protein length: 571-769a.a.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.

Gene Information

• Gene Name: CHSY3 chondroitin sulfate synthase 3 [ Homo sapiens (human) ]
• Official Symbol: CHSY3
• Synonyms: CHSY3; chondroitin sulfate synthase 3; CHSY2; CSS3; N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase 3; N-acetylgalactosaminyltransferase 3; carbohydrate synthase 2; chSy-2; chondroitin glucuronyltransferase 3; chondroitin synthase 2; chondroitin synthase-2; glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase II; HGNC:24293; Ensembl:ENSG00000198108; HPRD:16766; MIM:609963; Vega:OTTHUMG00000163043
• Gene ID: 337876
• mRNA Refseq: NM_175856.4
• Protein Refseq: NP_787052.3
• MIM: 609963
• UniProt ID: Q70JA7
• Chromosome Location: 5q23.3
• Pathway: Chondroitin sulfate biosynthesis, organism-specific biosystem; Chondroitin sulfate/dermatan sulfate metabolism, organism-specific biosystem; Disease, organism-specific biosystem; Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate, organism-specific biosystem; Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate, conserved biosystem; Glycosaminoglycan biosynthesis, chondroitin sulfate backbone, organism-specific biosystem; Glycosaminoglycan biosynthesis, chondroitin sulfate backbone, conserved biosystem
• Function: N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity; glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity; metal ion binding