Recombinant Human CLDN19 Protein, Myc/DDK-tagged, C13 and N15-labeled

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Recombinant Human CLDN19 Protein, Myc/DDK-tagged, C13 and N15-labeled

CLDN19 Related Products

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Cat.No. : CLDN19-2623H
Product Overview : CLDN19 MS Standard C13 and N15-labeled recombinant protein (NP_001116867) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
Description : The product of this gene belongs to the claudin family. It plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. Defects in this gene are the cause of hypomagnesemia renal with ocular involvement (HOMGO). HOMGO is a progressive renal disease characterized by primary renal magnesium wasting with hypomagnesemia, hypercalciuria and nephrocalcinosis associated with severe ocular abnormalities such as bilateral chorioretinal scars, macular colobomata, significant myopia and nystagmus. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 21.9 kDa
AA Sequence : MANSGLQLLG YFLALGGWVG IIASTALPQW KQSSYAGDAI ITAVGLYEGL WMSCASQSTG QVQCKLYDSL LALDGHIQSA RALMVVAVLL GFVAMVLSVV GMKCTRVGDS NPIAKGRVAI AGGALFILAG LCTLTAVSWY ATLVTQEFFN PSTPVNARYE FGPALFVGWA SAGLAVLGGS FLCCTCPEPE RPNSSPQPYR PGPSAAAREY VTRTRPLEQK LISEEDLAAN DILDYKDDDD KV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
SDS-PAGE :

Gene Name : CLDN19 claudin 19 [ Homo sapiens (human) ]
Official Symbol : CLDN19
Synonyms : CLDN19; claudin 19; HOMG5; claudin-19
Gene ID : 149461
mRNA Refseq : NM_001123395
Protein Refseq : NP_001116867
MIM : 610036
UniProt ID : Q8N6F1

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