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Recombinant Human CLEC10A Protein, GST-tagged

Cat.No. : CLEC10A-1451H
Product Overview : Human CLEC10A full-length ORF ( AAH39011, 1 a.a. - 316 a.a.) recombinant protein with GST-tag at N-terminal.
  • Specification
  • Gene Information
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Description : This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The encoded type 2 transmembrane protein may function as a cell surface antigen. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 60.5 kDa
AA Sequence : MTRTYENFQYLENKVKVQGFKNGPL PLQSLLQRLCSGPCHLLLSLGLGLL LLVIICVVGFQNSKFQRDLVTLRTD FSNFTSNTVAEIQALTSQGSSLEET IASLKAEVEGFKQERQAGVSELQEH TTQKAHLGHCPHCPSVCVPVHSEML LRVQQLVQDLKKLTCQVATLNNNAS TEGTCCPVNWVEHQDSCYWFSHSGM SWAEAEKYCQLKNAHLVVINSREEQ NFVQKYLGSAYTWMGLSDPEGAWKW VDGTDYATGFQNWKPGQPDDWQGHG LGGGEDCAHFHPDGRWNDDVCQRPY HWVCEAGLGQTSQESH
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene Name : CLEC10A C-type lectin domain family 10, member A [ Homo sapiens ]
Official Symbol : CLEC10A
Synonyms : CLEC10A; C-type lectin domain family 10, member A; C type (calcium dependent, carbohydrate recognition domain) lectin, superfamily member 14 (macrophage derived) , CLECSF13, CLECSF14; C-type lectin domain family 10 member A; CD301; HML; HML2; macrophage lectin 2 (calcium dependent); C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 13 (macrophage-derived); C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 14 (macrophage-derived); MGL; CLECSF13; CLECSF14;
Gene ID : 10462
mRNA Refseq : NM_006344
Protein Refseq : NP_006335
MIM : 605999
UniProt ID : Q8IUN9

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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Can CLEC10A protein be targeted for immunotherapy? 03/16/2020

Researchers are exploring the potential of targeting CLEC10A to modulate immune responses against cancer and infectious diseases, with the aim of developing novel immunotherapies.

How does CLEC10A protein interact with the immune system? 03/20/2019

CLEC10A functions as a receptor on immune cells, where it can recognize specific glycan structures on pathogens and tumor cells, leading to immune cell activation and modulation of immune responses.

What are the potential clinical implications of modulating CLEC10A activity? 12/16/2018

Modulating CLEC10A activity could have therapeutic implications for cancer immunotherapy, infectious disease treatment, and potentially other immune-related disorders.

How does CLEC10A protein impact the tumor microenvironment? 07/15/2018

CLEC10A expression on tumor-associated macrophages and dendritic cells can influence the immune response within the tumor microenvironment, potentially impacting tumor growth and metastasis.

Is CLEC10A protein expressed in specific cell types? 02/21/2018

CLEC10A is primarily expressed on dendritic cells and macrophages in the immune system, where it plays a role in antigen presentation and immune regulation.

Customer Reviews (3)

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Reviews
04/30/2022

    The CLEC10A protein exhibits remarkable performance in Western blotting (WB) experiments.

    01/07/2020

      The versatility and efficacy of CLEC10A in these applications make it an invaluable tool for researchers.

      09/17/2018

        Researchers can rely on CLEC10A to deliver reliable and accurate results in ELISA experiments, ensuring precise measurement and quantification of target proteins.

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