Recombinant Human CLEC10A Protein, GST-tagged
Cat.No. : | CLEC10A-1451H |
Product Overview : | Human CLEC10A full-length ORF ( AAH39011, 1 a.a. - 316 a.a.) recombinant protein with GST-tag at N-terminal. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The encoded type 2 transmembrane protein may function as a cell surface antigen. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008] |
Source : | Wheat Germ |
Species : | Human |
Tag : | GST |
Molecular Mass : | 60.5 kDa |
AA Sequence : | MTRTYENFQYLENKVKVQGFKNGPL PLQSLLQRLCSGPCHLLLSLGLGLL LLVIICVVGFQNSKFQRDLVTLRTD FSNFTSNTVAEIQALTSQGSSLEET IASLKAEVEGFKQERQAGVSELQEH TTQKAHLGHCPHCPSVCVPVHSEML LRVQQLVQDLKKLTCQVATLNNNAS TEGTCCPVNWVEHQDSCYWFSHSGM SWAEAEKYCQLKNAHLVVINSREEQ NFVQKYLGSAYTWMGLSDPEGAWKW VDGTDYATGFQNWKPGQPDDWQGHG LGGGEDCAHFHPDGRWNDDVCQRPY HWVCEAGLGQTSQESH |
Applications : | Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | CLEC10A C-type lectin domain family 10, member A [ Homo sapiens ] |
Official Symbol : | CLEC10A |
Synonyms : | CLEC10A; C-type lectin domain family 10, member A; C type (calcium dependent, carbohydrate recognition domain) lectin, superfamily member 14 (macrophage derived) , CLECSF13, CLECSF14; C-type lectin domain family 10 member A; CD301; HML; HML2; macrophage lectin 2 (calcium dependent); C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 13 (macrophage-derived); C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 14 (macrophage-derived); MGL; CLECSF13; CLECSF14; |
Gene ID : | 10462 |
mRNA Refseq : | NM_006344 |
Protein Refseq : | NP_006335 |
MIM : | 605999 |
UniProt ID : | Q8IUN9 |
Products Types
◆ Recombinant Protein | ||
CLEC10A-2681H | Recombinant Human CLEC10A Protein, His (Fc)-Avi-tagged | +Inquiry |
CLEC10A-1450H | Recombinant Human CLEC10A Protein | +Inquiry |
Clec10a-6908M | Recombinant Mouse Clec10a protein(Gln58-Ser305), hFc-tagged | +Inquiry |
CLEC10A-306H | Recombinant Human CLEC10A Protein, MYC/DDK-tagged, C13 and N15-labeled | +Inquiry |
CLEC10A-3238H | Recombinant Human CLEC10A Protein, MYC/DDK-tagged | +Inquiry |
◆ Lysates | ||
CLEC10A-1456HCL | Recombinant Human CLEC10A cell lysate | +Inquiry |
CLEC10A-1730MCL | Recombinant Mouse CLEC10A cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionResearchers are exploring the potential of targeting CLEC10A to modulate immune responses against cancer and infectious diseases, with the aim of developing novel immunotherapies.
CLEC10A functions as a receptor on immune cells, where it can recognize specific glycan structures on pathogens and tumor cells, leading to immune cell activation and modulation of immune responses.
Modulating CLEC10A activity could have therapeutic implications for cancer immunotherapy, infectious disease treatment, and potentially other immune-related disorders.
CLEC10A expression on tumor-associated macrophages and dendritic cells can influence the immune response within the tumor microenvironment, potentially impacting tumor growth and metastasis.
CLEC10A is primarily expressed on dendritic cells and macrophages in the immune system, where it plays a role in antigen presentation and immune regulation.
Customer Reviews (3)
Write a reviewThe CLEC10A protein exhibits remarkable performance in Western blotting (WB) experiments.
The versatility and efficacy of CLEC10A in these applications make it an invaluable tool for researchers.
Researchers can rely on CLEC10A to deliver reliable and accurate results in ELISA experiments, ensuring precise measurement and quantification of target proteins.
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