Recombinant Human CLEC4C Protein (45-213 aa), His-tagged CLEC4C-2074H

Recombinant Human CLEC4C Protein (45-213 aa), His-tagged

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Recombinant Human CLEC4C Protein (45-213 aa), His-tagged

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Cat.No. : CLEC4C-2074H
Product Overview : Recombinant Human CLEC4C Protein (45-213 aa) is produced by Yeast expression system. This protein is fused with a 6xHis tag at the N-terminal. Protein Description: Partial.
Description : Involved in antigen-capturing. Target ligand into antigen processing and peptide-loading compartments for presentation to T-cells. May mediate potent inhibition of induction of IFN-alpha/beta expression in plasmacytoid dendritic cells. May act as a signaling receptor that activates protein-tyrosine kinases and mobilizes intracellular calcium. Does not seem to bind mannose.
Source : Yeast
Species : Human
Tag : His
Form : Tris-based buffer,50% glycerol
Molecular Mass : 22.0 kDa
Protein length : 45-213 aa
AA Sequence : NFMYSKTVKRLSKLR EYQQYHPSLTCVMEG KDIEDWSCCPTPWTS FQSSCYFISTGMQSW TKSQKNCSVMGADLV VINTREEQDFIIQNL KRNSSYFLGLSDPGG RRHWQWVDQTPYNEN VTFWHSGEPNNLDER CAIINFRSSEEWGWN DIHCHVPQKSICKMK KIYI
Purity : > 90% as determined by SDS-PAGE.
Notes : Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week.
Storage : The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade.
Concentration : A hardcopy of COA with reconstitution instruction is sent along with the products.
Figure :

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

Gene Name : CLEC4C C-type lectin domain family 4, member C [ Homo sapiens ]
Official Symbol : CLEC4C
Synonyms : DLEC; HECL; BDCA2; CD303; CLECSF7; CLECSF11; PRO34150;
Gene ID : 170482
mRNA Refseq : NM_203503.1
Protein Refseq : NP_987099.1
MIM : 606677
UniProt ID : Q8WTT0

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