Recombinant Human CLK1
| Cat.No. : | CLK1-27274TH |
| Product Overview : | Recombinant full length Human CLK1 with N terminal proprietary tag, predicted mwt: 79.31 kDa. |
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| Species : | Human |
| Source : | Wheat Germ |
| Tag : | Non |
| Protein Length : | 484 amino acids |
| Description : | This gene encodes a member of the CDC2-like (or LAMMER) family of dual specificity protein kinases. In the nucleus, the encoded protein phosphorylates serine/arginine-rich proteins involved in pre-mRNA processing, releasing them into the nucleoplasm. The choice of splice sites during pre-mRNA processing may be regulated by the concentration of transacting factors, including serine/arginine rich proteins. Therefore, the encoded protein may play an indirect role in governing splice site selection. Multiple transcript variants encoding different isoforms have been found for this gene. |
| Molecular Weight : | 79.310kDa inclusive of tags |
| Form : | Liquid |
| Purity : | Proprietary Purification |
| Storage buffer : | pH: 8.00Constituents:0.3% Glutathione, 0.79% Tris HCl |
| Storage : | Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles. |
| Sequences of amino acids : | MRHSKRTYCPDWDDKDWDYGKWRSSSSHKRRKRSHSSAQE NKRCKYNHSKMCDSHYLESRSINEKDYHSRRYIDEYRNDY TQGCEPGHRQRDHESRYQNHSSKSSGRSGRSSYKSKHRIH HSTSHRRSHGKSHRRKRTRSVEDDEEGHLICQSGDVLSAR YEIVDTLGEGAFGKVVECIDHKAGGRHVAVKIVKNVDRYC EAARSEIQVLEHLNTTDPNSTFRCVQMLEWFEHHGHICIV FELLGLSTYDFIKENGFLPFRLDHIRKMAYQICKSVNFLH SNKLTHTDLKPENILFVQSDYTEAYNPKIKRDERTLINPD IKVVDFGSATYDDEHHSTLVSTRHYRAPEVILALGWSQPC DVWSIGCILIEYYLGFTVFPTHDSKEHLAMMERILGPLPK HMIQKTRKRKYFHHDRLDWDEHSSAGRYVSRRCKPLKEFM LSQDVEHERLFDLIQKMLEYDPAKRITLREALKHPFFDLL KKSI |
| Sequence Similarities : | Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. Lammer subfamily.Contains 1 protein kinase domain. |
| Gene Name | CLK1 CDC-like kinase 1 [ Homo sapiens ] |
| Official Symbol | CLK1 |
| Synonyms | CLK1; CDC-like kinase 1; dual specificity protein kinase CLK1; |
| Gene ID | 1195 |
| mRNA Refseq | NM_001162407 |
| Protein Refseq | NP_001155879 |
| MIM | 601951 |
| Uniprot ID | P49759 |
| Chromosome Location | 2q33 |
| Pathway | Legionellosis, organism-specific biosystem; Legionellosis, conserved biosystem; mRNA processing, organism-specific biosystem; |
| Function | ATP binding; non-membrane spanning protein tyrosine kinase activity; nucleotide binding; protein serine/threonine kinase activity; protein serine/threonine/tyrosine kinase activity; |
Not For Human Consumption!
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