Recombinant Human CLPS Protein, Myc/DDK-tagged, C13 and N15-labeled

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Recombinant Human CLPS Protein, Myc/DDK-tagged, C13 and N15-labeled

CLPS Related Products

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Cat.No. : CLPS-1844H
Product Overview : CLPS MS Standard C13 and N15-labeled recombinant protein (NP_001823) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
Description : The protein encoded by this gene is a cofactor needed by pancreatic lipase for efficient dietary lipid hydrolysis. It binds to the C-terminal, non-catalytic domain of lipase, thereby stabilizing an active conformation and considerably increasing the overall hydrophobic binding site. The gene product allows lipase to anchor noncovalently to the surface of lipid micelles, counteracting the destabilizing influence of intestinal bile salts. This cofactor is only expressed in pancreatic acinar cells, suggesting regulation of expression by tissue-specific elements. Three transcript variants encoding different isoforms have been found for this gene.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 12 kDa
AA Sequence : MEKILILLLV ALSVAYAAPG PRGIIINLEN GELCMNSAQC KSNCCQHSSA LGLARCTSMA SENSECSVKT LYGIYYKCPC ERGLTCEGDK TIVGSITNTN FGICHDAGRS KQTRTRPLEQ KLISEEDLAA NDILDYKDDD DKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
SDS-PAGE :

Gene Name : CLPS colipase [ Homo sapiens (human) ]
Official Symbol : CLPS
Synonyms : CLPS; colipase; colipase; colipase, pancreatic; pancreatic colipase preproprotein
Gene ID : 1208
mRNA Refseq : NM_001832
Protein Refseq : NP_001823
MIM : 120105
UniProt ID : P04118

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