Recombinant Human CMBL Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: CMBL-4919H
• Product Overview: CMBL MS Standard C13 and N15-labeled recombinant protein (NP_620164) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: CMBL (EC 3.1.1.45) is a cysteine hydrolase of the dienelactone hydrolase family that is highly expressed in liver cytosol. CMBL preferentially cleaves cyclic esters, and it activates medoxomil-ester prodrugs in which the medoxomil moiety is linked to an oxygen atom.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 28 kDa
• AA Sequence: MANEAYPCPCDIGHRLEYGGLGREV QVEHIKAYVTKSPVDAGKAVIVIQD IFGWQLPNTRYIADMISGNGYTTIV PDFFVGQEPWDPSGDWSIFPEWLKT RNAQKIDREISAILKYLKQQCHAQK IGIVGFCWGGTAVHHLMMKYSEFRA GVSVYGIVKDSEDIYNLKNPTLFIF AENDVVIPLKDVSLLTQKLKEHCKV EYQIKTFSGQTHGFVHRKREDCSPA DKPYIDEARRNLIEWLNKYMTRTRP LEQKLISEEDLAANDILDYKDDDDK V
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: CMBL carboxymethylenebutenolidase homolog [ Homo sapiens (human) ]
• Official Symbol: CMBL
• Synonyms: CMBL; carboxymethylenebutenolidase homolog (Pseudomonas); carboxymethylenebutenolidase like (Pseudomonas); carboxymethylenebutenolidase homolog; FLJ23617; carboxymethylenebutenolidase-like (Pseudomonas); JS-1
• Gene ID: 134147
• mRNA Refseq: NM_138809
• Protein Refseq: NP_620164
• MIM: 613379
• UniProt ID: Q96DG6