Recombinant Human CNOT11 Protein, MYC/DDK-tagged

• Cat.No.: CNOT11-3271H
• Product Overview: Recombinant Human CNOT11 protein, fused to MYC/DDK-tagged at C-terminus, was expressed in HEK293.

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Is required for the association of CNOT10 with the CCR4-NOT complex. Seems not to be required for complex deadenylase function.
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 55 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: CNOT11 CCR4-NOT transcription complex subunit 11 [ Homo sapiens ]
• Official Symbol: CNOT11
• Synonyms: C2orf29; C40
• Gene ID: 55571
• mRNA Refseq: NM_017546.4
• Protein Refseq: NP_060016