| Description : |
This gene encodes a protein that is a component of the conserved oligomeric Golgi (COG) complex, a multiprotein complex that plays a structural role in the Golgi apparatus, and is involved in intracellular membrane trafficking and glycoprotein modification. Mutations in this gene cause congenital disorder of glycosylation, type IIh, a disease that is characterized by under-glycosylated serum proteins, and whose symptoms include severe psychomotor retardation, failure to thrive, seizures, and dairy and wheat product intolerance. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
68.4 kDa |
| AA Sequence : |
MATAATIPSVATATAAALGEVEDEG LLASLFRDRFPEAQWRERPDVGRYL RELSGSGLERLRREPERLAEERAQL LQQTRDLAFANYKTFIRGAECTERI HRLFGDVEASLGRLLDRLPSFQQSC RNFVKEAEEISSNRRMNSLTLNRHT EILEILEIPQLMDTCVRNSYYEEAL ELAAYVRRLERKYSSIPVIQGIVNE VRQSMQLMLSQLIQQLRTNIQLPAC LRVIGYLRRMDVFTEAELRVKFLQA RDAWLRSILTAIPNDDPYFHITKTI EASRVHLFDIITQYRAIFSDEDPLL PPAMGEHTVNESAIFHGWVLQKVSQ FLQVLETDLYRGIGGHLDSLLGQCM YFGLSFSRVGADFRGQLAPVFQRVA ISTFQKAIQETVEKFQEEMNSYMLI SAPAILGTSNMPAAVPATQPGTLQP PMVLLDFPPLACFLNNILVAFNDLR LCCPVALAQDVTGALEDALAKVTKI ILAFHRAEEAAFSSGEQELFVQFCT VFLEDLVPYLNRCLQVLFPPAQIAQ TLGIPPTQLSKYGNLGHVNIGAIQE PLAFILPKRETLFTLDDQALGPELT APAPEPPAEEPRLEPAGPACPEGGR AETQAEPPSVGPTRTRPLEQKLISE EDLAANDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
