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Recombinant Human COIL Protein, GST-tagged

Cat.No. : COIL-1633H
Product Overview : Human COIL full-length ORF (BAG36378.1, 1 a.a. - 576 a.a.) recombinant protein with GST-tag at N-terminal.
  • Specification
  • Gene Information
  • Related Products
Description : The protein encoded by this gene is an integral component of Cajal bodies (also called coiled bodies). Cajal bodies are nuclear suborganelles of varying number and composition that are involved in the post-transcriptional modification of small nuclear and small nucleolar RNAs. The N-terminus of the coilin protein directs its self-oligomerization while the C-terminus influences the number of nuclear bodies assembled per cell. Differential methylation and phosphorylation of coilin likely influences its localization among nuclear bodies and the composition and assembly of Cajal bodies. This gene has pseudogenes on chromosome 4 and chromosome 14. [provided by RefSeq, Jul 2008]
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 89 kDa
AA Sequence : MAASETVRLRLQFDYPPPATPHCTA FWLLVDLNRCRVVTDLISLIRQRFG FSSGAFLGLYLEGGLLPPAESARLV RDNDCLRVKLEERGVAENSVVISNG DINLSLRKAKKRAFQLEEGEETEPD CKYSKKHWKSRENNNNNEKVLDLEP KAVTDQTVSKKNKRKNKATCGTVGD DNEEAKRKSPKKKEKCEYKKKAKNP KSPKVQAVKDWANQRCSSPKGSARN SLVKAKRKGSVSVCSKESPSSSSES ESCDESISDGPSKVTLEARNSSEKL PTELSKEEPSTKNTTADKLAIKLGF SLTPSKGKTSGTTSSSSDSSAESDD QCLMSSSTPECAAGFLKTVGLFAGR GRPGPGLSSQTAGAAGWRRSGSNGG GQAPGASPSVSLPASLGRGWGREEN LFSWKGAKGRGMRGRGRGRGHPVSC VVNRSTDNQRQQQLNDVVKNSSTII QNPVETPKKDYSLLPLLAAAPQVGE KIAFKLLELTSSYSPDVSDYKEGRI LSHNPETQQVDIEILSSLPALREPG KFDLVYHNENGAEVVEYAVTQESKI TVFWKELIDPRLIIESPSNTSSTEP A
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene Name : COIL coilin [ Homo sapiens ]
Official Symbol : COIL
Synonyms : COIL; coilin; CLN80; p80 coilin; p80; coilin p80; p80-coilin;
Gene ID : 8161
mRNA Refseq : NM_004645
Protein Refseq : NP_004636
MIM : 600272
UniProt ID : P38432

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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