Recombinant Human COL4A3BP Protein, GST-tagged

• Cat.No.: COL4A3BP-1652H
• Product Overview: Human COL4A3BP full-length ORF ( NP_112729.1, 1 a.a. - 598 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a kinase that specifically phosphorylates the N-terminal region of the non-collagenous domain of the alpha 3 chain of type IV collagen, known as the Goodpasture antigen. Goodpasture disease is the result of an autoimmune response directed at this antigen. One isoform of this protein is also involved in ceramide intracellular transport. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 94.4 kDa
• AA Sequence: MSDNQSWNSSGSEEDPETESGPPVE RCGVLSKWTNYIHGWQDRWVVLKNN ALSYYKSEDETEYGCRGSICLSKAV ITPHDFDECRFDISVNDSVWYLRAQ DPDHRQQWIDAIEQHKTESGYGSES SLRRHGSMVSLVSGASGYSATSTSS FKKGHSLREKLAEMETFRDILCRQV DTLQKYFDACADAVSKDELQRDKVV EDDEDDFPTTRSDGDFLHSTNGNKE KLFPHVTPKGINGIDFKGEAITFKA TTAGILATLSHCIELMVKREDSWQK RLDKETEKKRRTEEAYKNAMTELKK KSHFGGPDYEEGPNSLINEEEFFDA VEAALDRQDKIEEQSQSEKVRLHWP TSLPSGDAFSSVGTHRFVQKVEEMV QNHMTYSLQDVGGDANWQLVVEEGE MKVYRREVEENGIVLDPLKATHAVK GVTGHEVCNYFWNVDVRNDWETTIE NFHVVETLADNAIIIYQTHKRVWPA SQRDVLYLSVIRKIPALTENDPETW IVCNFSVDHDSAPLNNRCVRAKINV AMICQTLVSPPEGNQEISRDNILCK ITYVANVNPGGWAPASVLRAVAKRE YPKFLKRFTSYVQEKTAGKPILF
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: COL4A3BP collagen, type IV, alpha 3 (Goodpasture antigen) binding protein [ Homo sapiens ]
• Official Symbol: COL4A3BP
• Synonyms: COL4A3BP; collagen, type IV, alpha 3 (Goodpasture antigen) binding protein; collagen type IV alpha-3-binding protein; ceramide transporter; CERT; GPBP; StAR related lipid transfer (START) domain containing 11; STARD11; hCERT; ceramide transfer protein; lipid-transfer protein CERTL; StAR-related lipid transfer (START) domain containing 11; CERTL; FLJ20597
• Gene ID: 10087
• mRNA Refseq: NM_001130105
• Protein Refseq: NP_001123577
• MIM: 604677
• UniProt ID: Q9Y5P4