Recombinant Human Collagen, Type XVIII, Alpha 1
Cat.No. : | COL18A1-4986H |
Product Overview : | Recombinant human COL18A1 was expressed in E.coli and purified by using conventional chromatography techniques. |
- Specification
- Gene Information
- Related Products
Cat. No. : | COL18A1-4986H |
Description : | Endostatin is a naturally occurring 20 kDa polypeptide derived from the C-terminal portion of type XVIII collagen. It functions as an anti-angiogenic cytokine that is expressed in various organs with the highest levels in liver, lung and kidney. Endostatin inhibits angiogenesis by blocking the pro-angiogenic activities of VEGF and FGF basic. |
Source : | Human |
Host : | E.coli |
Form : | Supplied as a lyophilized powder. |
Purity : | >98% pure by SDS PAGE and HPLC |
Sequence : | Region of Endostatin protein corresponding to amino acids MHSHRDFQPV LHLVALNSPL SGGMRGIRGA DFQCFQQARA VGLAGTFRAF LSSRLQDLYS IVRRADRAAV PIVNLKDELL FPSWEALFSG SEGPLKPGAR IFSFDGKDVL RHPTWPQKSV WHGSDPNGRR LTESYCETWR TEAPSATGQA SSLLGGRLLG QSAASCHHAY IVLCIENSFM |
Molecular Mass : | 20.2 kDa |
Applications : | Numerous applications are possible with this product and should be tested by the end user under their own laboratory conditions |
Storage : | Store at 4 deg C until reconstitution. Following reconstitution aliquot and freeze at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles. |
Gene Name : | COL18A1 collagen, type XVIII, alpha 1 [ Homo sapiens ] |
Official Symbol : | COL18A1 |
Synonyms : | COL18A1; collagen, type XVIII, alpha 1; KNO; KNO1; FLJ27325; FLJ34914; MGC74745; collagen alpha-1(XVIII) chain; endostatin; antiangiogenic agent; multi-functional protein MFP |
Gene ID : | 80781 |
mRNA Refseq : | NM_030582 |
Protein Refseq : | NP_085059 |
MIM : | 120328 |
UniProt ID : | P39060 |
Chromosome Location : | 21q22.3 |
Pathway : | Direct p53 effector; FOXA1 transcription factor network; Protein digestion and absorption |
Function : | extracellular matrix structural constituent; metal ion binding; protein binding |
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Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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