Recombinant Human COQ3 Protein, GST-tagged
Cat.No. : | COQ3-1715H |
Product Overview : | Human COQ3 full-length ORF ( AAH63463.1, 1 a.a. - 369 a.a.) recombinant protein with GST-tag at N-terminal. |
- Specification
- Gene Information
- Related Products
Description : | Ubiquinone, also known as coenzyme Q, or Q, is a critical component of the electron transport pathways of both eukaryotes and prokaryotes (Jonassen and Clarke, 2000 [PubMed 10777520]). This lipid consists of a hydrophobic isoprenoid tail and a quinone head group. The tail varies in length depending on the organism, but its purpose is to anchor coenzyme Q to the membrane. The quinone head group is responsible for the activity of coenzyme Q in the respiratory chain. The S. cerevisiae COQ3 gene encodes an O-methyltransferase required for 2 steps in the biosynthetic pathway of coenzyme Q. This enzyme methylates an early coenzyme Q intermediate, 3,4-dihydroxy-5-polyprenylbenzoic acid, as well as the final intermediate in the pathway, converting demethyl-ubiquinone to coenzyme Q. The COQ3 gene product is also capable of methylating the distinct prokaryotic early intermediate 2-hydroxy-6-polyprenyl phenol.[supplied by OMIM, Mar 2008] |
Source : | Wheat Germ |
Species : | Human |
Tag : | GST |
Molecular Mass : | 67.4 kDa |
AA Sequence : | MWSGRKLGSSGGWFLRVLGPGGCNT KAARPLISSAVYVKNQLSGTLQIKP GVFNEYRTIWFKSYRTIFSCLNRIK SFRYPWARLYSTSQTTVDSGEVKTF LALAHKWWDEQGVYAPLHSMNDLRV PFIRDNLLKTIPNHQPGKPLLGMKI LDVGCGGGLLTEPLGRLGASVIGID PVDENIKTAQCHKSFDPVLDKRIEY RVCSLEEIVEETAETFDAVVASEVV EHVIDLETFLQCCCQVLKPGGSLFI TTINKTQLSYALGIVFSEQIAGIVP KGTHTWEKFVSPETLESILESNGLS VQTVVGMLYNPFSGYWHWSENTSLN YAAHAVKSRVQEHPASAEFVLKGET EELQANACTNPAVHEKLKK |
Applications : | Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | COQ3 coenzyme Q3 homolog, methyltransferase (S. cerevisiae) [ Homo sapiens ] |
Official Symbol : | COQ3 |
Synonyms : | COQ3; coenzyme Q3 homolog, methyltransferase (S. cerevisiae); coenzyme Q3 homolog, methyltransferase (yeast); hexaprenyldihydroxybenzoate methyltransferase, mitochondrial; bA9819.1; polyprenyldihydroxybenzoate methyltransferase; DHHB-MT; DHHB-MTase; DHHB methyltransferase; methyltransferase COQ3; 2-polyprenyl-6-hydroxyphenyl methylase; 3-demethylubiquinone-10 3-methyltransferase; dihydroxyhexaprenylbenzoate methyltransferase; 3,4-dihydroxy-5-hexaprenylbenzoate methyltransferase; DHHBMT; DHHBMTASE; UG0215E05; |
Gene ID : | 51805 |
mRNA Refseq : | NM_017421 |
Protein Refseq : | NP_059117 |
MIM : | 605196 |
UniProt ID : | Q9NZJ6 |
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◆ Lysates | ||
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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