Recombinant Human COQ8A Protein, GST-Tagged

• Cat.No.: COQ8A-0253H
• Product Overview: Human CABC1 full-length ORF (AAH05171, 1 a.a. - 647 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Species: Human
• Source: Wheat Germ
• Tag: GST
• Description: This gene encodes a mitochondrial protein similar to yeast ABC1, which functions in an electron-transferring membrane protein complex in the respiratory chain. It is not related to the family of ABC transporter proteins. Expression of this gene is induced by the tumor suppressor p53 and in response to DNA damage, and inhibiting its expression partially suppresses p53-induced apoptosis. Alternatively spliced transcript variants have been found; however, their full-length nature has not been determined. [provided by RefSeq, Jul 2008]
• Molecular Mass: 96.91 kDa
• AA Sequence: MAAILGDTIMVAKGLVKLTQAAVETHLQHLGIGGELIMAARALQSTAVEQIGMFLGKVQGQDKHEEYFAENFGGPEGEFHFSVPHAAGASTDFSSASAPDQSAPPSLGHAHSEGPAPAYVASGPFREAGFPGQASSPLGRANGRLFANPRDSFSAMGFQRRFFHQDQSPVGGLTAEDIEKARQAKARPENKQHKQTLSEHARERKVPVTRIGRLANFGGLAVGLGFGALAEVAKKSLRSEDPSGKKAVLGSSPFLSEANAERIVRTLCKVRGAALKLGQMLSIQDDAFINPHLAKIFERVRQSADFMPLKQMMKTLNNDLGPNWRDKLEYFEERPFAAASIGQVHLARMKGGREVAMKIQYPGVAQSINSDVNNLMAVLNMSNMLPEGLFPEHLIDVLRRELALECDYQREAACARKFRDLLKGHPFFYVPEIVDELCSPHVLTTELVSGFPLDQAEGLSQEIRNEICYNILVLCLRELFEFHFMQTDPNWSNFFYDPQQHKVALLDFGATREYDRSFTDLYIQIIRAAADRDRETVRAKSIEMKFLTGYEVKVMEDAHLDAILILGEAFASDEPFDFGTQSTTEKIHNLIPVMLRHRLVPPPEETYSLHRKMGGSFLICSKLKARFPCKAMFEEAYSNYCKRQAQQ
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: COQ8A coenzyme Q8A [ Homo sapiens (human) ]
• Official Symbol: COQ8A
• Synonyms: COQ8A; coenzyme Q8A; CABC1; chaperone, ABC1 activity of bc1 complex like (S. pombe); CABC1, chaperone, ABC1 activity of bc1 complex homolog (S. pombe), chaperone, ABC1 activity of bc1 complex like (S. pombe), chaperone ABC1 (activity of bc1 complex, S.pombe) like; coenzyme Q8 homolog (yeast); COQ8; SCAR9; Coenzyme Q8A; AarF Domain-Containing Protein Kinase 3; Coenzyme Q Protein 8A; Chaperone, ABC1 Activity Of Bc1 Complex Homolog (S. Pombe); Chaperone, ABC1 Activity Of Bc1 Complex Like (S. Pombe); Chaperone-ABC1 (Activity Of Bc1 Complex, S.Pombe)-Like; Chaperone Activity Of Bc1 Complex-Like, Mitochondrial; Chaperone, ABC1 Activity Of Bc1 Complex Homolog; Chaperone Activity Of Bc1 Complex-Like; Atypical Kinase ADCK3, Mitochondrial; Atypical Kinase COQ8A, Mitochondrial; AarF Domain Containing Kinase 3; Coenzyme Q8 Homolog (Yeast); Coenzyme Q8 Homolog; Chaperone-ABC1-Like; EC 2.7.-.-; EC 2.7.11
• Gene ID: 56997
• mRNA Refseq: NM_020247
• Protein Refseq: NP_064632
• MIM: 606980
• UniProt ID: Q8NI60