Recombinant Human COQ8A Protein, GST-Tagged

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Recombinant Human COQ8A Protein, GST-Tagged

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Specification Gene Information
Cat.No. : COQ8A-0253H
Product Overview : Human CABC1 full-length ORF (AAH05171, 1 a.a. - 647 a.a.) recombinant protein with GST-tag at N-terminal.
Description : This gene encodes a mitochondrial protein similar to yeast ABC1, which functions in an electron-transferring membrane protein complex in the respiratory chain. It is not related to the family of ABC transporter proteins. Expression of this gene is induced by the tumor suppressor p53 and in response to DNA damage, and inhibiting its expression partially suppresses p53-induced apoptosis. Alternatively spliced transcript variants have been found; however, their full-length nature has not been determined. [provided by RefSeq, Jul 2008]
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 96.91 kDa
AA Sequence : MAAILGDTIM VAKGLVKLTQ AAVETHLQHL GIGGELIMAA RALQSTAVEQ IGMFLGKVQG QDKHEEYFAE NFGGPEGEFH FSVPHAAGAS TDFSSASAPD QSAPPSLGHA HSEGPAPAYV ASGPFREAGF PGQASSPLGR ANGRLFANPR DSFSAMGFQR RFFHQDQSPV GGLTAEDIEK ARQAKARPEN KQHKQTLSEH ARERKVPVTR IGRLANFGGL AVGLGFGALA EVAKKSLRSE DPSGKKAVLG SSPFLSEANA ERIVRTLCKV RGAALKLGQM LSIQDDAFIN PHLAKIFERV RQSADFMPLK QMMKTLNNDL GPNWRDKLEY FEERPFAAAS IGQVHLARMK GGREVAMKIQ YPGVAQSINS DVNNLMAVLN MSNMLPEGLF PEHLIDVLRR ELALECDYQR EAACARKFRD LLKGHPFFYV PEIVDELCSP HVLTTELVSG FPLDQAEGLS QEIRNEICYN ILVLCLRELF EFHFMQTDPN WSNFFYDPQQ HKVALLDFGA TREYDRSFTD LYIQIIRAAA DRDRETVRAK SIEMKFLTGY EVKVMEDAHL DAILILGEAF ASDEPFDFGT QSTTEKIHNL IPVMLRHRLV PPPEETYSLH RKMGGSFLIC SKLKARFPCK AMFEEAYSNY CKRQAQQ
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Quality Control Testing :

12.5% SDS-PAGE Stained with Coomassie Blue.
Gene Name : COQ8A coenzyme Q8A [ Homo sapiens (human) ]
Official Symbol : COQ8A
Synonyms : COQ8A; coenzyme Q8A; CABC1; chaperone, ABC1 activity of bc1 complex like (S. pombe); CABC1, chaperone, ABC1 activity of bc1 complex homolog (S. pombe), chaperone, ABC1 activity of bc1 complex like (S. pombe), chaperone ABC1 (activity of bc1 complex, S.pombe) like; coenzyme Q8 homolog (yeast); COQ8; SCAR9; Coenzyme Q8A; AarF Domain-Containing Protein Kinase 3; Coenzyme Q Protein 8A; Chaperone, ABC1 Activity Of Bc1 Complex Homolog (S. Pombe); Chaperone, ABC1 Activity Of Bc1 Complex Like (S. Pombe); Chaperone-ABC1 (Activity Of Bc1 Complex, S.Pombe)-Like; Chaperone Activity Of Bc1 Complex-Like, Mitochondrial; Chaperone, ABC1 Activity Of Bc1 Complex Homolog; Chaperone Activity Of Bc1 Complex-Like; Atypical Kinase ADCK3, Mitochondrial; Atypical Kinase COQ8A, Mitochondrial; AarF Domain Containing Kinase 3; Coenzyme Q8 Homolog (Yeast); Coenzyme Q8 Homolog; Chaperone-ABC1-Like; EC 2.7.-.-; EC 2.7.11
Gene ID : 56997
mRNA Refseq : NM_020247
Protein Refseq : NP_064632
MIM : 606980
UniProt ID : Q8NI60

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