Recombinant Human COX7C, GST-tagged

Cat.No. : COX7C-11503H
Product Overview : Recombinant Human COX7C protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.
Availability July 23, 2024
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Description : Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes subunit VIIc, which shares 87% and 85% amino acid sequence identity with mouse and bovine COX VIIc, respectively, and is found in all tissues. A pseudogene COX7CP1 has been found on chromosome 13.
Source : E.coli
Species : Human
Tag : GST
Protein length : 1-63a.a.
Storage : The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer : 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.
Gene Name : COX7C cytochrome c oxidase subunit VIIc [ Homo sapiens ]
Official Symbol : COX7C
Synonyms : COX7C; COX7C_HUMAN; Cytochrome c oxidase polypeptide VIIc; Cytochrome c oxidase subunit 7C; mitochondrial; cytochrome-c oxidase chain VIIc; Cytochrome c oxidase polypeptide VIIc
Gene ID : 1350
mRNA Refseq : NM_001867.2
Protein Refseq : NP_001858.1
MIM : 603774
UniProt ID : P15954
Chromosome Location : 5q14
Pathway : Alzheimers disease, organism-specific biosystem; Alzheimers disease, conserved biosystem; Cardiac muscle contraction, organism-specific biosystem; Cardiac muscle contraction, conserved biosystem; Cytochrome c oxidase, organism-specific biosystem; Cytochrome c oxidase, conserved biosystem; Electron Transport Chain, organism-specific biosystem;
Function : cytochrome-c oxidase activity;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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