| Description : |
This gene encodes a member of the M14 family of metallocarboxypeptidases. The encoded preproprotein is proteolytically processed to generate the mature peptidase. This peripheral membrane protein cleaves C-terminal amino acid residues and is involved in the biosynthesis of peptide hormones and neurotransmitters, including insulin. This protein may also function independently of its peptidase activity, as a neurotrophic factor that promotes neuronal survival, and as a sorting receptor that binds to regulated secretory pathway proteins, including prohormones. Mutations in this gene are implicated in type 2 diabetes. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
His |
| Form : |
Lyophilized |
| Molecular Mass : |
49 kDa |
| Protein length : |
476 |
| AA Sequence : |
MAGRGGSALLALCGALAACGWLLGA EAQEPGAPAAGMRRRRRLQQEDGIS FEYHRYPELREALVSVWLQCTAISR IYTVGRSFEGRELLVIELSDNPGVH EPGEPEFKYIGNMHGNEAVGRELLI FLAQYLCNEYQKGNETIVNLIHSTR IHIMPSLNPDGFEKAASQPGELKDW FVGRSNAQGIDLNRNFPDLDRIVYV NEKEGGPNNHLLKNMKKIVDQNTKL APETKAVIHWIMDIPFVLSANLHGG DLVANYPYDETRSGSAHEYSSSPDD AIFQSLARAYSSFNPAMSDPNRPPC RKNDDDSSFVDGTTNGGAWYSVPGG MQDFNYLSSNCFEITVELSCEKFPP EETLKTYWEDNKNSLISYLEQIHRG VKGFVRDLQGNPIANATISVEGIDH DVTSAKDGDYWRLLIPGNYKLTASA PGYLAITKKVAVPYSPAAGVDFELE SFSERKEEEKEELMEWWKMMSETLN F |
| Purity : |
> 98% |
| Applications : |
WB; ELISA; FACS; FC |
| Stability : |
This bioreagent is stable at 4 centigrade (short-term) and -70 centigrade(long-term). After reconstitution, sample may be stored at 4 centigrade for 2-7 days and below -18 centigrade for future use. |
| Storage : |
At -20 centigrade. |
| Concentration : |
1 mg/mL |
| Storage Buffer : |
PBS (pH 7.4-7.5). Sterile-filtered colorless solution. |
| Reconstitution : |
Reconstitute in sterile distilled H2O to no less than 100 μg/mL; dilute reconstituted stock further in other aqueous solutions if needed. Please review COA for lot-specific instructions. Final measurements should be determined by the end-user for optimal performance. |
