Recombinant Human CPSF3 Protein, Myc/DDK-tagged, C13 and N15-labeled

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Recombinant Human CPSF3 Protein, Myc/DDK-tagged, C13 and N15-labeled

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Cat.No. : CPSF3-1458H
Product Overview : CPSF3 MS Standard C13 and N15-labeled recombinant protein (NP_057291) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
Description : This gene encodes a member of the metallo-beta-lactamase family. The encoded protein is a 73kDa subunit of the cleavage and polyadenylation specificity factor and functions as an endonuclease that recognizes the pre-mRNA 3'-cleavage site AAUAAA prior to polyadenylation. It also cleaves after the pre-mRNA sequence ACCCA during histone 3'-end pre-mRNA processing.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 77.5 kDa
AA Sequence : MSAIPAEESD QLLIRPLGAG QEVGRSCIIL EFKGRKIMLD CGIHPGLEGM DALPYIDLID PAEIDLLLIS HFHLDHCGAL PWFLQKTSFK GRTFMTHATK AIYRWLLSDY VKVSNISADD MLYTETDLEE SMDKIETINF HEVKEVAGIK FWCYHAGHVL GAAMFMIEIA GVKLLYTGDF SRQEDRHLMA AEIPNIKPDI LIIESTYGTH IHEKREEREA RFCNTVHDIV NRGGRGLIPV FALGRAQELL LILDEYWQNH PELHDIPIYY ASSLAKKCMA VYQTYVNAMN DKIRKQININ NPFVFKHISN LKSMDHFDDI GPSVVMASPG MMQSGLSREL FESWCTDKRN GVIIAGYCVE GTLAKHIMSE PEEITTMSGQ KLPLKMSVDY ISFSAHTDYQ QTSEFIRALK PPHVILVHGE QNEMARLKAA LIREYEDNDE VHIEVHNPRN TEAVTLNFRG EKLAKVMGFL ADKKPEQGQR VSGILVKRNF NYHILSPCDL SNYTDLAMST VKQTQAIPYT GPFNLLCYQL QKLTGDVEEL EIQEKPALKV FKNITVIQEP GMVVLEWLAN PSNDMYADTV TTVILEVQSN PKIRKGAVQK VSKKLEMHVY SKRLEIMLQD IFGEDCVSVK DDSILSVTVD GKTANLNLET RTVECEEGSE DDESLREMVE LAAQRLYEAL TPVHTRTRPL EQKLISEEDL AANDILDYKD DDDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
SDS-PAGE :

Gene Name : CPSF3 cleavage and polyadenylation specific factor 3 [ Homo sapiens (human) ]
Official Symbol : CPSF3
Synonyms : CPSF3; cleavage and polyadenylation specific factor 3, 73kDa; cleavage and polyadenylation specific factor 3, 73kD subunit; cleavage and polyadenylation specificity factor subunit 3; CPSF 73; CPSF73; YSH1; CPSF 73 kDa subunit; mRNA 3-end-processing endonuclease CPSF-73; cleavage and polyadenylation specificity factor 3; cleavage and polyadenylation specificity factor 73 kDa subunit; CPSF; CPSF-73;
Gene ID : 51692
mRNA Refseq : NM_016207
Protein Refseq : NP_057291
MIM : 606029
UniProt ID : Q9UKF6

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