Recombinant Human CPSF6 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: CPSF6-876H
• Product Overview: CPSF6 MS Standard C13 and N15-labeled recombinant protein (NP_008938) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: The protein encoded by this gene is one subunit of a cleavage factor required for 3' RNA cleavage and polyadenylation processing. The interaction of the protein with the RNA is one of the earliest steps in the assembly of the 3' end processing complex and facilitates the recruitment of other processing factors. The cleavage factor complex is composed of four polypeptides. This gene encodes the 68kD subunit. It has a domain organization reminiscent of spliceosomal proteins.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 59.2 kDa
• AA Sequence: MADGVDHIDIYADVGEEFNQEAEYG GHDQIDLYDDVISPSANNGDAPEDR DYMDTLPPTVGDDVGKGAAPNVVYT YTGKRIALYIGNLTWWTTDEDLTEA VHSLGVNDILEIKFFENRANGQSKG FALVGVGSEASSKKLMDLLPKRELH GQNPVVTPCNKQFLSQFEMQSRKTT QSGQMSGEGKAGPPGGSSRAAFPQG GRGRGRFPGAVPGGDRFPGPAGPGG PPPPFPAGQTPPRPPLGPPGPPGPP GPPPPGQVLPPPLAGPPNRGDRPPP PVLFPGQPFGQPPLGPLPPGPPPPV PGYGPPPGPPPPQQGPPPPPGPFPP RPPGPLGPPLTLAPPPHLPGPPPGA PPPAPHVNPAFFPPPTNSGMPTSDS RGPPPTDPYGRPPPYDRGDYGPPGR EMDTARTPLSEAEFEEIMNRNRAIS SSAISRAVSDASAGDYGSAIETLVT AISLIKQSKVSADDRCKVLISSLQD CLHGIESKSYGSGSRRERSRERDHS RSREKSRRHKSRSRDRHDDYYRERS RERERHRDRDRDRDRERDREREYRH RTRTRPLEQKLISEEDLAANDILDY KDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: CPSF6 cleavage and polyadenylation specific factor 6 [ Homo sapiens (human) ]
• Official Symbol: CPSF6
• Synonyms: CPSF6; cleavage and polyadenylation specific factor 6, 68kDa; cleavage and polyadenylation specific factor 6, 68kD subunit; cleavage and polyadenylation specificity factor subunit 6; CFIM; CFIM68; HPBRII 4; HPBRII 7; protein HPBRII-4/7; CPSF 68 kDa subunit; pre-mRNA cleavage factor Im (68kD); pre-mRNA cleavage factor I, 68kD subunit; pre-mRNA cleavage factor Im 68 kDa subunit; cleavage and polyadenylation specificity factor 68 kDa subunit; HPBRII-4; HPBRII-7
• Gene ID: 11052
• mRNA Refseq: NM_007007
• Protein Refseq: NP_008938
• MIM: 604979
• UniProt ID: Q16630