Recombinant Human CRHR2 Protein, GST-tagged

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Recombinant Human CRHR2 Protein, GST-tagged

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Cat.No. : CRHR2-1870H
Product Overview : Human CRHR2 full-length ORF ( NP_001874.2, 1 a.a. - 411 a.a.) recombinant protein with GST-tag at N-terminal.
Description : The protein encoded by this gene belongs to the G-protein coupled receptor 2 family, and the subfamily of corticotropin releasing hormone receptor. This receptor shows high affinity for corticotropin releasing hormone (CRH), and also binds CRH-related peptides such as urocortin. CRH is synthesized in the hypothalamus, and plays an important role in coordinating the endocrine, autonomic, and behavioral responses to stress and immune challenge. Studies in mice suggest that this receptor maybe involved in mediating cardiovascular homeostasis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jan 2011]
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 74.1 kDa
AA Sequence : MDAALLHSLL EANCSLALAE ELLLDGWGPP LDPEGPYSYC NTTLDQIGTC WPRSAAGALV ERPCPEYFNG VKYNTTRNAY RECLENGTWA SKINYSQCEP ILDDKQRKYD LHYRIALVVN YLGHCVSVAA LVAAFLLFLA LRSIRCLRNV IHWNLITTFI LRNVMWFLLQ LVDHEVHESN EVWCRCITTI FNYFVVTNFF WMFVEGCYLH TAIVMTYSTE RLRKCLFLFI GWCIPFPIIV AWAIGKLYYE NEQCWFGKEP GDLVDYIYQG PIILVLLINF VFLFNIVRIL MTKLRASTTS ETIQYRKAVK ATLVLLPLLG ITYMLFFVNP GEDDLSQIMF IYFNSFLQSF QGFFVSVFYC FFNGEVRSAV RKRWHRWQDH HSLRVPMARA MSIPTSPTRI SFHSIKQTAA V
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Quality Control Testing: :

12.5% SDS-PAGE Stained with Coomassie Blue.

Gene Name : CRHR2 corticotropin releasing hormone receptor 2 [ Homo sapiens ]
Official Symbol : CRHR2
Synonyms : CRHR2; corticotropin releasing hormone receptor 2; corticotropin-releasing factor receptor 2; CRF RB; CRF2; HM CRF; CRH-R2; CRF2 receptor, beta isoform; CRFR2; CRF-RB; HM-CRF;
Gene ID : 1395
mRNA Refseq : NM_001202475
Protein Refseq : NP_001189404
MIM : 602034
UniProt ID : Q13324
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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