Recombinant Human CRKL Protein, Myc/DDK-tagged, C13 and N15-labeled

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Recombinant Human CRKL Protein, Myc/DDK-tagged, C13 and N15-labeled

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Cat.No. : CRKL-6088H
Product Overview : CRKL MS Standard C13 and N15-labeled recombinant protein (NP_005198) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
Description : This gene encodes a protein kinase containing SH2 and SH3 (src homology) domains which has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS-dependent fashion. It is a substrate of the BCR-ABL tyrosine kinase, plays a role in fibroblast transformation by BCR-ABL, and may be oncogenic.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 33.6 kDa
AA Sequence : MSSARFDSSD RSAWYMGPVS RQEAQTRLQG QRHGMFLVRD SSTCPGDYVL SVSENSRVSH YIINSLPNRR FKIGDQEFDH LPALLEFYKI HYLDTTTLIE PAPRYPSPPM GSVSAPNLPT AEDNLEYVRT LYDFPGNDAE DLPFKKGEIL VIIEKPEEQW WSARNKDGRV GMIPVPYVEK LVRSSPHGKH GNRNSNSYGI PEPAHAYAQP QTTTPLPAVS GSPGAAITPL PSTQNGPVFA KAIQKRVPCA YDKTALALEV GDIVKVTRMN INGQWEGEVN GRKGLFPFTH VKIFDPQNPD ENETRTRPLE QKLISEEDLA ANDILDYKDD DDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
SDS-PAGE :

Gene Name : CRKL CRK like proto-oncogene, adaptor protein [ Homo sapiens (human) ]
Official Symbol : CRKL
Synonyms : CRKL; v-crk sarcoma virus CT10 oncogene homolog (avian)-like; v crk avian sarcoma virus CT10 oncogene homolog like; crk-like protein;
Gene ID : 1399
mRNA Refseq : NM_005207
Protein Refseq : NP_005198
MIM : 602007
UniProt ID : P46109

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