Recombinant Human CRTC3 protein, GST-tagged
Cat.No. : | CRTC3-32H |
Product Overview : | Recombinant Human CRTC3(176 a.a. - 274 a.a.) fused with GST tag at N-terminal was expressed in Wheat Germ. |
- Specification
- Gene Information
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Description : | This gene is a member of the CREB regulated transcription coactivator gene family. This family regulates CREB-dependent gene transcription in a phosphorylation-independent manner and may be selective for cAMP-responsive genes. The protein encoded by this gene may induce mitochondrial biogenesis and attenuate catecholamine signaling in adipose tissue. A translocation event between this gene and Notch coactivator mastermind-like gene 2, which results in a fusion protein, has been reported in mucoepidermoid carcinomas. Alternative splicing results in multiple transcript variants that encode different protein isoforms. |
Source : | Wheat Germ |
Species : | Human |
Tag : | GST |
Form : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Molecular Mass : | 36.63 kDa |
AA Sequence : | QDPYGGGGQSAWPAPYMGFCDGENN GHGEVASFPGPLKEENLLNVPKPLP KQLWETKEIQSLSGRPRSCDVGGGN AFPHNGQNLGLSPFLGTLNTGGSL |
Applications : | Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Gene Name : | CRTC3 CREB regulated transcription coactivator 3 [ Homo sapiens ] |
Official Symbol : | CRTC3 |
Synonyms : | CRTC3; CREB regulated transcription coactivator 3; CREB-regulated transcription coactivator 3; FLJ21868; TORC-3; transducer of CREB protein 3; transducer of regulated CREB protein 3; transducer of regulated cAMP response element-binding protein 3; transducer of regulated cAMP response element-binding protein (CREB) 3; TORC3; |
Gene ID : | 64784 |
mRNA Refseq : | NM_022769 |
Protein Refseq : | NP_073606 |
MIM : | 608986 |
UniProt ID : | Q6UUV7 |
Chromosome Location : | 15q26.1 |
Pathway : | HTLV-I infection, organism-specific biosystem; HTLV-I infection, conserved biosystem; |
Function : | cAMP response element binding protein binding; |
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Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionModulating CRTC3 activity has shown promise as a potential therapeutic approach for treating metabolic diseases, though more research is needed.
CRTC3 is involved in glucose homeostasis by influencing the expression of genes related to gluconeogenesis and glucose uptake.
Research suggests that targeting CRTC3 may have therapeutic potential in certain cancers, but further studies are required to validate this approach.
The potential diagnostic applications of CRTC3 are still under exploration, but its altered expression levels may serve as biomarkers for certain conditions.
Modulating CRTC3 activity may hold promise for neuroprotective strategies, but the specific mechanisms and applications require more investigation.
Customer Reviews (3)
Write a reviewThe CRTC3 protein's versatility extends beyond its use in vitro experiments.
With the CRTC3 protein as a research tool, achieving meaningful scientific findings becomes an accessible and achievable goal.
Their expertise and dedication enable them to effectively address and resolve any technical issues that may arise during experimentation.
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