Active Recombinant Human CSF2 Protein

• Cat.No.: CSF2-1968H
• Product Overview: Human CSF2 (127 a.a.) full-lenth recombinant protein expressed in Barley grain (Hordeum vulgare). This protein is endotoxins-free and thus optimal to use in stem cell cultures.

Specification

• Description: The protein encoded by this gene is a cytokine that controls the production, differentiation, and function of granulocytes and macrophages. The active form of the protein is found extracellularly as a homodimer. This gene has been localized to a cluster of related genes at chromosome region 5q31, which is known to be associated with interstitial deletions in the 5q- syndrome and acute myelogenous leukemia. Other genes in the cluster include those encoding interleukins 4, 5, and 13. [provided by RefSeq, Jul 2008]
• Source: Plants
• Species: Human
• Form: Lyophilized
• Bio-activity: Activity has been measured by cell-based proliferation assay using TF-1 cells. ED50 is 0.05 ng/mL.
• Molecular Mass: 30, 38 kDa
• Endotoxin: Endotoxin level is less than 0.005ng per ug (0.05EU/μg) as measured by LAL assay.
• Purity: > 95% by SDS-PAGE
• Applications: Western Blot (Recombinant protein)
  Functional Study
  SDS-PAGE
• Storage: Store at -20 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: Lyophilized from PBS, pH 7.2

Gene Information

• Gene Name: CSF2 colony stimulating factor 2 (granulocyte-macrophage) [ Homo sapiens ]
• Official Symbol: CSF2
• Synonyms: CSF2; colony stimulating factor 2 (granulocyte-macrophage); granulocyte-macrophage colony-stimulating factor; GM CSF; GMCSF; granulocyte macrophage colony stimulating factor; molgramostin; sargramostim; CSF; colony-stimulating factor; granulocyte-macrophage colony stimulating factor; MGC131935; MGC138897
• Gene ID: 1437
• mRNA Refseq: NM_000758
• Protein Refseq: NP_000749
• MIM: 138960
• UniProt ID: P04141