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Recombinant Human CSF3R Protein (25-620 aa), GST-tagged

Cat.No. : CSF3R-1251H
Product Overview : Recombinant Human CSF3R Protein (25-620 aa) is produced by E. coli expression system. This protein is fused with a GST tag at the N-terminal. Research Area: Cancer. Protein Description: Partial.
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  • Gene Information
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Description : Cytokine that stimulates the growth and differentiation of hatopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes.
Source : E. coli
Species : Human
Tag : GST
Form : Tris-based buffer,50% glycerol
Molecular Mass : 93.5 kDa
Protein length : 25-620 aa
AA Sequence : ECGHISVSAPIVHLGDPITASCIIK QNCSHLDPEPQILWRLGAELQPGGR QQRLSDGTQESIITLPHLNHTQAFL SCCLNWGNSLQILDQVELRAGYPPA IPHNLSCLMNLTTSSLICQWEPGPE THLPTSFTLKSFKSRGNCQTQGDSI LDCVPKDGQSHCCIPRKHLLLYQNM GIWVQAENALGTSMSPQLCLDPMDV VKLEPPMLRTMDPSPEAAPPQAGCL QLCWEPWQPGLHINQKCELRHKPQR GEASWALVGPLPLEALQYELCGLLP ATAYTLQIRCIRWPLPGHWSDWSPS LELRTTERAPTVRLDTWWRQRQLDP RTVQLFWKPVPLEEDSGRIQGYVVS WRPSGQAGAILPLCNTTELSCTFHL PSEAQEVALVAYNSAGTSRPTPVVF SESRGPALTRLHAMARDPHSLWVGW EPPNPWPQGYVIEWGLGPPSASNSN KTWRMEQNGRATGFLLKENIRPFQL YEIIVTPLYQDTMGPSQHVYAYSQE MAPSHAPELHLKHIGKTWAQLEWVP EPPELGKSPLTHYTIFWTNAQNQSF SAILNASSRGFVLHGLEPASLYHIH LMAASQAGATNSTVLTLMTLT
Purity : > 90% as determined by SDS-PAGE.
Notes : Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week.
Storage : The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade.
Concentration : A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
Gene Name : CSF3R colony stimulating factor 3 receptor (granulocyte) [ Homo sapiens ]
Official Symbol : CSF3R
Synonyms : CSF3R; CD114; GCSFR; G-CSF-R; CD114 antigen; G-CSF receptor;
Gene ID : 1441
mRNA Refseq : NM_000760
Protein Refseq : NP_000751
MIM : 138971
UniProt ID : Q99062

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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In which conditions are CSF3R-targeted therapies currently being investigated? 11/22/2021

CSF3R-targeted therapies are under investigation for conditions such as chronic neutrophilic leukemia and other myeloproliferative neoplasms.

Are there specific diagnostic tests for CSF3R mutations? 08/11/2021

Yes, genetic testing and sequencing techniques are commonly employed to identify CSF3R mutations and guide clinical decision-making.

How do CSF3R mutations impact the prognosis of hematological disorders? 12/29/2019

The presence and specific type of CSF3R mutations can influence the prognosis of hematological disorders, guiding clinicians in predicting disease progression and response to treatment.

Can CSF3R mutations be hereditary? 04/12/2019

Yes, some CSF3R mutations can be hereditary, leading to familial cases of neutropenia.

How does understanding CSF3R protein function contribute to treatment strategies? 02/08/2018

Targeted therapies directed at CSF3R may offer more effective and tailored treatment options for patients with disorders related to abnormal granulocyte production.

Customer Reviews (3)

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Reviews
06/23/2019

    the CSF3R protein demonstrates exceptional stability, allowing for prolonged storage and usage without compromising its integrity.

    12/07/2018

      the protein's high quality ensures accurate and reliable results, enabling precise analysis and interpretation of experimental data.

      09/16/2018

        The manufacturer of the CSF3R protein plays a crucial role in supporting researchers during their trials.

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