Recombinant Human CTS protein, His-tagged

• Cat.No.: CTS-H5224
• Product Overview: Recombinant Human CTS protein (Gln17-Ile331), fused to His tag at C-terminus, was expressed in human 293 cells (HEK293).

Specification

• Species: Human
• Source: HEK293
• Tag: His
• Protein Length: 315
• Description: Cathepsin S is also known as CTSS, which is a member of the peptidase C1 family. Cathepsin S is a lysosomal cysteine protease that may participate in the degradation of antigenic proteins to peptides for presentation on MHC class II molecules. Cathepsin S can function as an elastase over a broad pH range in alveolar macrophages. The catalytic activity of cathepsin S is similar to cathepsin L, but with much less activity on Z-Phe-Arg-|-NHMec, and more activity on the Z-Val-Val-Arg-|-Xaa compound.
• Form: Lyophilized from 0.22 um filtered solution in 50 mM MES, 100 mM NaCl, pH6.5, 10% trehalose.
• Molecular Mass: The protein has a calculated MW of 36.6 kDa. The protein migrates as 36-42 kDa (pro) and 26 kDa (mature) under reducing (R) condition (SDS-PAGE) due to glycosylation.
• Endotoxin: Less than 1.0 EU per ug by the LAL method.
• Purity: >95% as determined by SDS-PAGE.
• Storage: For long term storage, the product should be stored at lyophilized state at -20 centigrade or lower.
  Please avoid repeated freeze-thaw cycles.
  This product is stable after storage at:
  -20 centigrade to -70 centigrade for 12 months in lyophilized state;
  -70 centigrade for 3 months under sterile conditions after reconstitution.
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents.

Gene Information

• Gene Name: CTSS
• Official Symbol: CTSS
• Synonyms: Cathepsin S
• Gene ID: 1520
• mRNA Refseq: NM_004079.5
• Protein Refseq: NP_004070.3
• MIM: 116845
• UniProt ID: P25774