| Cat.No. : |
CTS-H5224 |
| Product Overview : |
Recombinant Human CTS protein (Gln17-Ile331), fused to His tag at C-terminus, was expressed in human 293 cells (HEK293). |
| Description : |
Cathepsin S is also known as CTSS, which is a member of the peptidase C1 family. Cathepsin S is a lysosomal cysteine protease that may participate in the degradation of antigenic proteins to peptides for presentation on MHC class II molecules. Cathepsin S can function as an elastase over a broad pH range in alveolar macrophages. The catalytic activity of cathepsin S is similar to cathepsin L, but with much less activity on Z-Phe-Arg-|-NHMec, and more activity on the Z-Val-Val-Arg-|-Xaa compound. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
His |
| Form : |
Lyophilized from 0.22 um filtered solution in 50 mM MES, 100 mM NaCl, pH6.5, 10% trehalose. |
| Molecular Mass : |
The protein has a calculated MW of 36.6 kDa. The protein migrates as 36-42 kDa (pro) and 26 kDa (mature) under reducing (R) condition (SDS-PAGE) due to glycosylation. |
| Protein length : |
315 |
| Endotoxin : |
Less than 1.0 EU per ug by the LAL method. |
| Purity : |
>95% as determined by SDS-PAGE. |
| Storage : |
For long term storage, the product should be stored at lyophilized state at -20 centigrade or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
-20 centigrade to -70 centigrade for 12 months in lyophilized state;
-70 centigrade for 3 months under sterile conditions after reconstitution. |
| Reconstitution : |
It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4ºC before opening to recover the entire contents. |
| SDS-PAGE of CTS-H5224 : |
Human Cathepsin S, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.