Recombinant Human CTS protein, His-tagged
|Product Overview :||Recombinant Human CTS protein (Gln17-Ile331), fused to His tag at C-terminus, was expressed in human 293 cells (HEK293).|
|Description :||Cathepsin S is also known as CTSS, which is a member of the peptidase C1 family. Cathepsin S is a lysosomal cysteine protease that may participate in the degradation of antigenic proteins to peptides for presentation on MHC class II molecules. Cathepsin S can function as an elastase over a broad pH range in alveolar macrophages. The catalytic activity of cathepsin S is similar to cathepsin L, but with much less activity on Z-Phe-Arg-|-NHMec, and more activity on the Z-Val-Val-Arg-|-Xaa compound.|
|Form :||Lyophilized from 0.22 um filtered solution in 50 mM MES, 100 mM NaCl, pH6.5, 10% trehalose.|
|Molecular Mass :||The protein has a calculated MW of 36.6 kDa. The protein migrates as 36-42 kDa (pro) and 26 kDa (mature) under reducing (R) condition (SDS-PAGE) due to glycosylation.|
|Protein length :||315|
|Endotoxin :||Less than 1.0 EU per ug by the LAL method.|
|Purity :||>95% as determined by SDS-PAGE.|
For long term storage, the product should be stored at lyophilized state at -20 centigrade or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
-20 centigrade to -70 centigrade for 12 months in lyophilized state;
-70 centigrade for 3 months under sterile conditions after reconstitution.
|Reconstitution :||It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4ºC before opening to recover the entire contents.|
|SDS-PAGE of CTS-H5224 :||
Human Cathepsin S, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
|Gene Name :||CTSS|
|Official Symbol :||CTSS|
|Synonyms :||Cathepsin S|
|Gene ID :||1520|
|mRNA Refseq :||NM_004079.5|
|Protein Refseq :||NP_004070.3|
|UniProt ID :||P25774|