- Human(1)
Recombinant Human CTS protein, His-tagged
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| Cat.No. : | CTS-H5224 |
| Product Overview : | Recombinant Human CTS protein (Gln17-Ile331), fused to His tag at C-terminus, was expressed in human 293 cells (HEK293). |
| Description : | Cathepsin S is also known as CTSS, which is a member of the peptidase C1 family. Cathepsin S is a lysosomal cysteine protease that may participate in the degradation of antigenic proteins to peptides for presentation on MHC class II molecules. Cathepsin S can function as an elastase over a broad pH range in alveolar macrophages. The catalytic activity of cathepsin S is similar to cathepsin L, but with much less activity on Z-Phe-Arg-|-NHMec, and more activity on the Z-Val-Val-Arg-|-Xaa compound. |
| Source : | HEK293 |
| Species : | Human |
| Tag : | His |
| Form : | Lyophilized from 0.22 um filtered solution in 50 mM MES, 100 mM NaCl, pH6.5, 10% trehalose. |
| Molecular Mass : | The protein has a calculated MW of 36.6 kDa. The protein migrates as 36-42 kDa (pro) and 26 kDa (mature) under reducing (R) condition (SDS-PAGE) due to glycosylation. |
| Protein length : | 315 |
| Endotoxin : | Less than 1.0 EU per ug by the LAL method. |
| Purity : | >95% as determined by SDS-PAGE. |
| Storage : |
For long term storage, the product should be stored at lyophilized state at -20 centigrade or lower. Please avoid repeated freeze-thaw cycles. This product is stable after storage at: -20 centigrade to -70 centigrade for 12 months in lyophilized state; -70 centigrade for 3 months under sterile conditions after reconstitution. |
| Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4ºC before opening to recover the entire contents. |
| SDS-PAGE of CTS-H5224 : |
Human Cathepsin S, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%. |
| Gene Name : | CTSS |
| Official Symbol : | CTSS |
| Synonyms : | Cathepsin S |
| Gene ID : | 1520 |
| mRNA Refseq : | NM_004079.5 |
| Protein Refseq : | NP_004070.3 |
| MIM : | 116845 |
| UniProt ID : | P25774 |
