Recombinant Human CTSD Protein, GST-tagged

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Recombinant Human CTSD Protein, GST-tagged

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Cat.No. : CTSD-2103H
Product Overview : Human CTSD full-length ORF ( AAH16320, 26 a.a. - 412 a.a.) recombinant protein with GST-tag at N-terminal.
Description : This gene encodes a member of the A1 family of peptidases. The encoded preproprotein is proteolytically processed to generate multiple protein products. These products include the cathepsin D light and heavy chains, which heterodimerize to form the mature enzyme. This enzyme exhibits pepsin-like activity and plays a role in protein turnover and in the proteolytic activation of hormones and growth factors. Mutations in this gene play a causal role in neuronal ceroid lipofuscinosis-10 and may be involved in the pathogenesis of several other diseases, including breast cancer and possibly Alzheimer's disease. [provided by RefSeq, Nov 2015]
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 71.06 kDa
AA Sequence : LHKFTSIRRT MSEVGGSVED LIAKGPVSKY SQAVPAVTEG PIPEVLKNYM DAQYYGEIGI GTPPQCFTVV FDTGSSNLWV PSIHCKLLDI ACWIHHKYNS DKSSTYVKNG TSFDIHYGSG SLSGYLSQDT VSVPCQSASS ASALGGVKVE RQVFGEATKQ PGITFIAAKF DGILGMAYPR ISVNNVLPVF DNLMQQKLVD QNIFSFYLSR DPDAQPGGEL MLGGTDSKYY KGSLSYLNVT RKAYWQVHLD QVEVASGLTL CKEGCEAIVD TGTSLMVGPV DEVRELQKAI GAVPLIQGEY MIPCEKVSTL PAITLKLGGK GYKLSPEDYT LKVSQAGKTL CLSGFMGMDI PPPSGPLWIL GDVFIGRYYT VFDRDNNRVG FAEAARL
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Quality Control Testing: :

12.5% SDS-PAGE Stained with Coomassie Blue.

Gene Name : CTSD cathepsin D [ Homo sapiens ]
Official Symbol : CTSD
Synonyms : CTSD; cathepsin D; cathepsin D (lysosomal aspartyl protease) , CPSD; ceroid lipofuscinosis; neuronal 10; CLN10; lysosomal aspartyl protease; lysosomal aspartyl peptidase; ceroid-lipofuscinosis, neuronal 10; CPSD; MGC2311;
Gene ID : 1509
mRNA Refseq : NM_001909
Protein Refseq : NP_001900
MIM : 116840
UniProt ID : P07339
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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