| Cat.No. : |
CTSD-2103H |
| Product Overview : |
Human CTSD full-length ORF ( AAH16320, 26 a.a. - 412 a.a.) recombinant protein with GST-tag at N-terminal. |
| Description : |
This gene encodes a member of the A1 family of peptidases. The encoded preproprotein is proteolytically processed to generate multiple protein products. These products include the cathepsin D light and heavy chains, which heterodimerize to form the mature enzyme. This enzyme exhibits pepsin-like activity and plays a role in protein turnover and in the proteolytic activation of hormones and growth factors. Mutations in this gene play a causal role in neuronal ceroid lipofuscinosis-10 and may be involved in the pathogenesis of several other diseases, including breast cancer and possibly Alzheimer's disease. [provided by RefSeq, Nov 2015] |
| Source : |
Wheat Germ |
| Species : |
Human |
| Tag : |
GST |
| Molecular Mass : |
71.06 kDa |
| AA Sequence : |
LHKFTSIRRT MSEVGGSVED LIAKGPVSKY SQAVPAVTEG PIPEVLKNYM DAQYYGEIGI GTPPQCFTVV FDTGSSNLWV PSIHCKLLDI ACWIHHKYNS DKSSTYVKNG TSFDIHYGSG SLSGYLSQDT VSVPCQSASS ASALGGVKVE RQVFGEATKQ PGITFIAAKF DGILGMAYPR ISVNNVLPVF DNLMQQKLVD QNIFSFYLSR DPDAQPGGEL MLGGTDSKYY KGSLSYLNVT RKAYWQVHLD QVEVASGLTL CKEGCEAIVD TGTSLMVGPV DEVRELQKAI GAVPLIQGEY MIPCEKVSTL PAITLKLGGK GYKLSPEDYT LKVSQAGKTL CLSGFMGMDI PPPSGPLWIL GDVFIGRYYT VFDRDNNRVG FAEAARL |
| Applications : |
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array |
| Notes : |
Best use within three months from the date of receipt of this protein. |
| Storage : |
Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
| Storage Buffer : |
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
| Quality Control Testing: : |
12.5% SDS-PAGE Stained with Coomassie Blue.
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.