Recombinant Human CTSD Protein, GST-tagged

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Recombinant Human CTSD Protein, GST-tagged

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Cat.No. : CTSD-2103H
Product Overview : Human CTSD full-length ORF ( AAH16320, 26 a.a. - 412 a.a.) recombinant protein with GST-tag at N-terminal.
Description : This gene encodes a member of the A1 family of peptidases. The encoded preproprotein is proteolytically processed to generate multiple protein products. These products include the cathepsin D light and heavy chains, which heterodimerize to form the mature enzyme. This enzyme exhibits pepsin-like activity and plays a role in protein turnover and in the proteolytic activation of hormones and growth factors. Mutations in this gene play a causal role in neuronal ceroid lipofuscinosis-10 and may be involved in the pathogenesis of several other diseases, including breast cancer and possibly Alzheimer's disease. [provided by RefSeq, Nov 2015]
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 71.06 kDa
AA Sequence : LHKFTSIRRTMSEVG GSVEDLIAKGPVSKY SQAVPAVTEGPIPEV LKNYMDAQYYGEIGI GTPPQCFTVVFDTGS SNLWVPSIHCKLLDI ACWIHHKYNSDKSST YVKNGTSFDIHYGSG SLSGYLSQDTVSVPC QSASSASALGGVKVE RQVFGEATKQPGITF IAAKFDGILGMAYPR ISVNNVLPVFDNLMQ QKLVDQNIFSFYLSR DPDAQPGGELMLGGT DSKYYKGSLSYLNVT RKAYWQVHLDQVEVA SGLTLCKEGCEAIVD TGTSLMVGPVDEVRE LQKAIGAVPLIQGEY MIPCEKVSTLPAITL KLGGKGYKLSPEDYT LKVSQAGKTLCLSGF MGMDIPPPSGPLWIL GDVFIGRYYTVFDRD NNRVGFAEAARL
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Quality Control Testing: :

12.5% SDS-PAGE Stained with Coomassie Blue.

Gene Name : CTSD cathepsin D [ Homo sapiens ]
Official Symbol : CTSD
Synonyms : CTSD; cathepsin D; cathepsin D (lysosomal aspartyl protease) , CPSD; ceroid lipofuscinosis; neuronal 10; CLN10; lysosomal aspartyl protease; lysosomal aspartyl peptidase; ceroid-lipofuscinosis, neuronal 10; CPSD; MGC2311;
Gene ID : 1509
mRNA Refseq : NM_001909
Protein Refseq : NP_001900
MIM : 116840
UniProt ID : P07339

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