Recombinant Human CTSD Protein, His (Fc)-Avi-tagged
|Product Overview :||Recombinant Human CTSD with His (Fc)-Avi tag was expressed and purified|
- Gene Information
- Related Products
|Tag :||His (Fc)-Avi|
|Endotoxin :||< 1.0 EU per μg of the protein as determined by the LAL method|
|Purity :||≥85% by SDS-PAGE|
|Stability :||Stable for at least 6 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.|
|Storage :||For long term storage, aliquot and store at -20 to -80 centigrade. Avoid repeated freezing and thawing cycles.|
|Storage Buffer :||PBS buffer|
|Gene Name :||CTSD cathepsin D [ Homo sapiens (human) ]|
|Official Symbol :||CTSD|
|Synonyms :||CTSD; cathepsin D; CPSD; CLN10; MGC2311; cathepsin D; lysosomal aspartyl protease; lysosomal aspartyl peptidase; ceroid-lipofuscinosis, neuronal 10; Cathepsin D; EC 22.214.171.124; OTTHUMP00000042282; OTTHUMP00000196039; OTTHUMP00000198692|
|Gene ID :||1509|
|mRNA Refseq :||NM_001909|
|Protein Refseq :||NP_001900|
|UniProt ID :||P07339|
|◆ Recombinant Protein|
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|Ctsd-2369M||Recombinant Mouse Ctsd Protein, His-tagged||+Inquiry|
|CTSD-786H||Recombinant Human CTSD Protein, His-tagged||+Inquiry|
|CTSD-913R||Recombinant Rhesus Macaque CTSD Protein, His (Fc)-Avi-tagged||+Inquiry|
|◆ Native Protein|
|CTSD-5325D||Active Native Human CTSD protein||+Inquiry|
|CTSD-1648H||Active Native Human Cathepsin D||+Inquiry|
|CTSD-189H||Active Native Human Cathepsin D||+Inquiry|
|CTSD-1735HCL||Recombinant Human CTSD cell lysate||+Inquiry|
|CTSD-3023MCL||Recombinant Mouse CTSD cell lysate||+Inquiry|
|◆ Assay kits|
|Kit-0264||Cathepsin D Inhibitor Screening Kit||+Inquiry|
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Q&As (6)Ask a question
There is an association between CTSD proteins and cognitive function. In some neurodegenerative diseases, abnormal accumulation and deposition of CTSD proteins may affect neuronal signaling and synaptic function, leading to a decline in cognitive function.
In some neurodegenerative diseases, levels of the CTSD protein may change. For example, people with Alzheimer's disease may have elevated levels of the CTSD protein. These changes may help in the diagnosis of the disease and in the assessment of the course of the disease.
For people with cognitive decline, their CTSD protein levels can be assessed by a blood or cerebrospinal fluid sample. This evaluation can help doctors understand whether the cause of cognitive decline is related to a neurodegenerative disease.
It is currently no treatment that directly targets the CTSD protein. However, some medications can reduce symptoms of neurodegenerative diseases, such as cholinesterase inhibitors such as donepezil, which can increase acetylcholine levels in synapses, which can improve cognitive function.
People with Parkinson's disease may have reduced levels of the CTSD protein. This decrease may be associated with neuronal death and impaired synaptic function. In addition, CTSD protein may also be associated with motor symptoms in patients with Parkinson's disease.
CTSD proteins play a role in Alzheimer's disease, Parkinson's disease, and other neurodegenerative diseases. It may change in these diseases, leading to structural alterations and impaired signaling of neuronal synapses.
Customer Reviews (3)Write a review
Good at western-blot experiments. -
In experiments, the biocompatibility performed well. -
The experimental conditions are broad, and the experimental results are accurate and repeatable. -
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