Recombinant Human CTSK Protein, GST-tagged

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Recombinant Human CTSK Protein, GST-tagged

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Cat.No. : CTSK-2111H
Product Overview : Human CTSK full-length ORF ( AAH16058, 15 a.a. - 329 a.a.) recombinant protein with GST-tag at N-terminal.
Description : The protein encoded by this gene is a lysosomal cysteine proteinase involved in bone remodeling and resorption. This protein, which is a member of the peptidase C1 protein family, is predominantly expressed in osteoclasts. However, the encoded protein is also expressed in a significant fraction of human breast cancers, where it could contribute to tumor invasiveness. Mutations in this gene are the cause of pycnodysostosis, an autosomal recessive disease characterized by osteosclerosis and short stature. [provided by RefSeq, Apr 2013]
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 60.28 kDa
AA Sequence : ALYPEEILDT HWELWKKTHR KQYNNKVDEI SRRLIWEKNL KYISIHNLEA SLGVHTYELA MNHLGDMTSE EVVQKMTGLK VPLSHSRSND TLYIPEWEGR APDSVDYRKK GYVTPVKNQG QCGSCWAFSS VGALEGQLKK KTGKLLNLSP QNLVDCVSEN DGCGGGYMTN AFQYVQKNRG IDSEDAYPYV GQEESCMYNP TGKAAKCRGY REIPEGNEKA LKRAVARVGP VSVAIDASLT SFQFYSKGVY YDESCNSDNL NHAVLAVGYG IQKGNKHWII KNSWGENWGN KGYILMARNK NNACGIANLA SFPKM
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Quality Control Testing: :

12.5% SDS-PAGE Stained with Coomassie Blue.

Gene Name : CTSK cathepsin K [ Homo sapiens ]
Official Symbol : CTSK
Synonyms : CTSK; cathepsin K; cathepsin K (pycnodysostosis) , CTSO, CTSO2, PYCD; PKND; cathepsin O; cathepsin X; cathepsin O1; cathepsin O2; CTSO; PYCD; CTS02; CTSO1; CTSO2; MGC23107;
Gene ID : 1513
mRNA Refseq : NM_000396
Protein Refseq : NP_000387
MIM : 601105
UniProt ID : P43235

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