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Recombinant Human CTSL Protein, MYC/DDK-tagged

Cat.No. : CTSL-3380H
Product Overview : Recombinant Human CTSL protein, fused to MYC/DDK-tagged at C-terminus, was expressed in HEK293.
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Description : The protein encoded by this gene is a lysosomal cysteine proteinase that plays a major role in intracellular protein catabolism. Its substrates include collagen and elastin, as well as alpha-1 protease inhibitor, a major controlling element of neutrophil elastase activity. The encoded protein has been implicated in several pathologic processes, including myofibril necrosis in myopathies and in myocardial ischemia, and in the renal tubular response to proteinuria. This protein, which is a member of the peptidase C1 family, is a dimer composed of disulfide-linked heavy and light chains, both produced from a single protein precursor. Multiple alternatively spliced transcript variants have been found for this gene.
Source : HEK293
Species : Human
Tag : MYC/DDK
Form : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Mass : 35.8 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration : >50 ug/mL as determined by microplate BCA method
Gene Name : Ctsl cathepsin L [ Mus musculus (house mouse) ]
Official Symbol : CTSL
Synonyms : CATL; CTSL1; MEP
Gene ID : 13039
mRNA Refseq : NM_009984.3
Protein Refseq : NP_034114.1
UniProt ID : P06797

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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