Recombinant Human CTTN, MYC/DDK-tagged
Cat.No. : |
CTTN-28H |
Product Overview : |
Recombinant Human CTTN, transcript variant 2, fused with C-terminal MYC/DDK, was expressed in HEK293 cells. |
- Specification
- Gene Information
- Related Products
Description : |
This gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. This gene has two roles: (1) regulating the interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase-dependent manner. The aberrant regulation of this gene contributes to tumor cell invasion and metastasis. Three splice variants that encode different isoforms have been identified for this gene. |
Source : |
HEK293 cells |
Species : |
Human |
Tag : |
MYC/DDK |
Molecular Mass : |
57.3 kDa |
Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
Concentration : |
>50 ug/mL as determined by microplate BCA method |
Storage Buffer : |
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name : |
CTTN cortactin [ Homo sapiens (human) ] |
Official Symbol : |
CTTN |
Synonyms : |
CTTN; cortactin; EMS1, ems1 sequence (mammary tumor and squamous cell carcinoma associated (p80/85 src substrate); src substrate cortactin |
Gene ID : |
2017 |
mRNA Refseq : |
NM_138565 |
Protein Refseq : |
NP_612632 |
MIM : |
164765 |
UniProt ID : |
Q14247 |
Chromosome Location : |
11q13 |
Pathway : |
Bacterial invasion of epithelial cells; FGF signaling pathway; Pathogenic Escherichia coli infection |
Function : |
protein binding |
Products Types
Related Gene
CTTN
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.